Helping pulmonology patients breathe better
Our pulmonology research team focuses on improving the health and care of patients with lung conditions. Those conditions include chronic obstructive pulmonary disease (COPD), asthma, lung nodules and sleep disorders. We collaborate with scientists in the Chronic Obstructive Pulmonary Disease Clinical Research Network (COPD CRN) on some of our studies.
There is no cure and relatively few new treatments for COPD and asthma. Our goals are to reduce symptoms and improve quality of life for those with lung conditions. We also aim to bring our pulmonology research into practice to deliver great care.
COPD CRN trials
We have participated in several clinical trials to explore treatment of COPD and reduction of COPD flare-ups (shortness of breath, producing more mucous):
- AMBOX (Ambulatory Oxygen) – Use of light weight oxygen to enable increased activity levels.
- MACRO (Macrolides for COPD) – Use of daily azithromycin (antibiotic) to reduce COPD flare-ups.
- STATCOPE (SimvaSTAT in the Prevention of COPD Exacerbations) – Use of simvastatin (cholesterol-lowering drug) for reducing COPD flare-ups.
- LEUKO (Leukotrienes for COPD) – Use of zileuton (asthma drug) to treat COPD flare-ups
- BLOCK_COPD (Beta-Blockers for the Prevention of Acute Exacerbations of COPD) – We are testing how well metoprolol succinate (beta blocker) taken once per day works to reduce COPD flare-ups for patients who have moderately severe COPD. We are also testing the effect of the drug on rates and severity of COPD flare-ups, cardiovascular events, death from all causes, lung function, exercise tolerance and quality of life. This is funded by the Department of Defense.