Antigliadin antibodies in Huntington's disease Journal Article uri icon
Overview
abstract
  • The relevance of gluten sensitivity in sporadic and hereditary ataxia pathogenesis is unclear. The authors found high antigliadin antibody titers in 23 of 52 (44%) patients with Huntington's disease (HD), suggesting a previously unrecognized association between HD and gluten sensitivity. The results further question "gluten ataxia" as a distinct disease entity and raise the possibility that antigliadin antibodies in ataxia and other neurodegenerative diseases may be an epiphenomenon, the mechanisms of which remain to be investigated.

  • Link to Article
    publication date
  • 2004
  • published in
  • Neurology  Journal
  • Research
    keywords
  • Antibodies/*blood
  • Gliadin/*immunology
  • Huntington Disease/blood/genetics/*immunology
  • Immunoglobulin A/*blood
  • Immunoglobulin G/*blood
  • Trinucleotide Repeat Expansion
  • Additional Document Info
    volume
  • 62
  • issue
  • 1