Therapy in Huntington's disease: where are we [review]? Review uri icon
  • As of 2012, almost 20 years after the discovery of the causative gene, clinical research has yet to find a disease-modifying treatment for Huntington's disease. However, both pharmacologic and nonpharmacologic therapies are available for many of the common symptoms of the disease. Recent studies of gene-positive patients in the prodromal, not clinically diagnosable, stages of the disease, are changing our perception of when the process of neurodegeneration begins. Once disease-modifying therapies become available, the approach to the diagnosis of Huntington's disease will likely shift from an examination-based clinical diagnosis, to one that includes a more complex combination of imaging, examination, and biomarker analysis.

  • Link to Article
    publication date
  • 2012
  • Research
  • Animal Studies
  • Dementia
  • Mental Disorders
  • Nervous System Diseases
  • Additional Document Info
  • 12
  • issue
  • 4