Lesbian, gay, bisexual, and other sexual minority (LGB+) travelers face risks similar to those of other travelers, influenced by age, sex, socioeconomic status, mental health considerations, and substance use, rather than sexual attraction or identity. LGB+ travelers face some unique risks, however, and healthcare professionals counseling them should tailor their advice accordingly. Healthcare professionals should advise LGB+ international travelers on being familiar with local laws, safety risks, and available resources.