Strong management and leadership skills create a positive workplace culture in which team members receive high quality mentoring and do work with a high level of productivity, quality, and efficiency. Although training in management and leadership is commonplace in many industries, it is rarely part of formal education or professional development in academia and other settings in which clinical research is conducted. This panel will focus on topics of interest to scientists who currently direct clinical research in behavioral medicine, or who are planning to do so in the future. The panel members will draw upon their years of experience serving as principal investigators and leaders of clinical research teams and will discuss challenges and best practices in three domains: 1) Putting together an A team: recruiting, selecting, and retaining outstanding research staff and trainees, 2) Mentoring and managing team members: setting the stage for high-quality work and training through inspiration, goal-setting, feedback, and effective meetings, and 3) Managing yourself: keys to staying energized, productive, and innovative as a leader. The moderator will provide the panel members with prompts and questions in these three areas and panel members will also take questions from the audience.