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Jonathan D. Alpern MD
Former Research Investigator

Academic appointment: Assistant Professor, Department of Medicine, Division of Infectious Diseases, University of Minnesota; Core faculty, University of Minnesota Global Health Course

Joined the Institute: 2017

Education and training: MD, Virginia Commonwealth University, Richmond, VA; residency in internal medicine, University of Minnesota Minneapolis; chief residency, Regions Hospital, St. Paul; fellowship in infectious diseases, University of Minnesota Minneapolis.

Overview/research interests: Dr. Alpern’s research interests include travel and tropical medicine, and the cost and availability of prescription drugs in the United States, with a focus on anti-infective drugs and low socioeconomic status populations.

Current research activities and funding:

• Sole-source, Off-patent Drugs in the United States: Prevalence, Pricing, and Populations Affected
• Stamaril Expanded Access Protocol



Publications While At HealthPartners
selected publications
Journal Article
  • Conflicts of interest among infectious diseases clinical practice guideline authors and the pharmaceutical industry
    JAMA network open. 2023
  • Costs of malaria treatment in the United States
    Journal of Travel Medicine. 2023
  • Evaluation of preferred language and timing of COVID-19 vaccine uptake and disease outcomes
    JAMA network open. 2023
  • Food and Drug Administration approval of artesunate for severe malaria: enough to achieve best practice?
    Clinical Infectious Diseases. 2023
  • Understanding COVID-19 health disparities with birth country and language data
    American Journal of Preventive Medicine. 2023
  • Antifungal drug price increases in the United States, 2000-2019
    Mycoses. 2022
  • Antimalarial chemoprophylaxis and treatment in the USA: limited access and extreme price variability
    Journal of Travel Medicine. 2022
  • Characteristics of state legislation addressing prescription drug price increases in the United States, 2020
    Journal of General Internal Medicine. 2022
  • Health care utilization in the 6 months following SARS-CoV-2 infection
    JAMA network open. 2022
  • Incidence of Guillain-Barré syndrome after COVID-19 vaccination in the Vaccine Safety Datalink
    JAMA network open. 2022
  • Low treatment rates of parasitic diseases with standard-of-care prescription drugs in the United States, 2013-2019
    American Journal of Tropical Medicine and Hygiene. 2022
  • Low use of standard-of-care antiparasitic drugs and increased estimated outpatient payments for treating schistosomiasis in the United States, 2013-19
    American Journal of Tropical Medicine and Hygiene. 2022
  • Trends in pricing and out-of-pocket spending on entecavir among commercially insured patients, 2014-2018
    JAMA network open. 2022
  • A 29-year-old with chronic abdominal pain; beyond helicobacter pylori
    Clinical Infectious Diseases. 2021
  • Drug-dispensing limits within Medicaid during the COVID-19 pandemic
    Journal of managed care & specialty pharmacy. 2021
  • Increases in anti-infective drug prices, subsequent prescribing, and outpatient costs
    JAMA network open. 2021
  • Population characteristics, use, and spending on sole-source, off-patent drugs among commercial insurance members in the United States—an analysis of outpatient claims data at a single health plan
    Journal of the American College of Clinical Pharmacy. 2021
  • The erosion of public trust and SARS-CoV-2 vaccines -more action is needed
    Open forum infectious diseases. 2021
  • Antiparasitic drugs in the United States--two roads to high prices
    Front Sociol. 2020
  • Barriers to malaria prevention among immigrant travelers in the United States who visit friends and relatives in sub-Saharan Africa: a cross-sectional, multi-setting survey of knowledge, attitudes, and practices
    PloS One. 2020
  • COVID-19 and dexamethasone: a potential strategy to avoid steroid-related strongyloides hyperinfection
    JAMA. 2020
  • Characteristics and price increases among sole-source, off-patent drugs in the United States, 2008 to 2018
    JAMA network open. 2020
  • Cutaneous leishmaniasis
    New England Journal of Medicine. 2020
  • Impact of anthelmintic price increases on practice patterns of healthcare providers caring for immigrant and refugee populations in the United States
    American Journal of Tropical Medicine and Hygiene. 2020
  • Improving hepatitis b care in the US: a case for a new "Ryan White" program
    Journal of Health Care for the Poor and Underserved. 2020
  • Off-label therapies for COVID-19--are we all in this together?
    Clinical Pharmacology and Therapeutics. 2020
  • Travel-associated chikungunya acquired in Myanmar in 2019
    Euro Surveillance. 2020
  • Broken drug markets in infectious diseases: opportunities outside the private sector?
    PLoS Neglected Tropical Diseases. 2019
  • Case report: epididymo-orchitis due to mycobacterium tuberculosis
    American Journal of Tropical Medicine and Hygiene. 2019
  • Prescription drug-dispensing limits in the USA-implications for malaria chemoprophylaxis among VFR travellers
    Journal of Travel Medicine. 2018
  • Access to benznidazole for Chagas disease in the United States-cautious optimism?
    PLoS Neglected Tropical Diseases. 2017
  • Incentives for bushmeat consumption and importation among West African immigrants, Minnesota, USA
    Emerging Infectious Diseases. 2017
  • Minocycline-induced skin hyperpigmentation
    Postgraduate Medical Journal. 2017
  • Prosthetic joint infection due to mycobacterium avium-intracellulare in a patient with rheumatoid arthritis: a case report and review of the literature
  • Strongyloides hyperinfection following hematopoietic stem cell transplant in a patient with HTLV-1-associated T-cell leukemia
    Transplant Infectious Disease. 2017
  • Trends in pricing and generic competition within the oral antibiotic drug market in the United States
    Clinical Infectious Diseases. 2017
  • Diagnostic delay and antibiotic overuse in acute pulmonary blastomycosis
    Open forum infectious diseases. 2016
  • Ozena in immigrants of differing backgrounds
    American Journal of Tropical Medicine and Hygiene. 2016
  • Perceived barriers to success for resident physicians interested in immigrant and refugee health
    BMC Medical Education. 2016
  • A closer view. The realities of practicing medicine in Tanzania
    Minnesota Medicine. 2014
  • High-cost generic drugs--implications for patients and policymakers
    New England Journal of Medicine. 2014
  • Variables associated with utilization of a centralized medical post in the Andean community of Pampas Grande, Peru
    Journal of Rural Health. 2012
  • Review
  • off patent drugs
    infectious disease
    travel medicine
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  • Jonathan D. Alpern, MD
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