Ella A. Chrenka M.S.
Manager of Statistical Services and Biostatistician
About

Ella Chrenka, MS, is a Biostatistician and manager of the Research Methodology Group at HealthPartners Institute. She earned her Master of Science in Biostatistics at the University of Minnesota graduating in 2019. Her focus areas include theory and application of statistical methods for quantitative analysis and approaches to clinical study design, with a specific interest in pragmatic trials. Ella provides statistical consulting services to investigators within the Health Partners Institute, the Neuroscience Research Centers and clinician-investigators working in critical care.

Conducting Institute research since 2019.

Education and training:
 
Master of Science, Biostatistics - University of Minnesota - Twin Cities
Bachelor of Arts, Speech-Language-Hearing Sciences - University of Minnesota - Twin Cities

Current research activities and funding:
Factors Associated with Healthcare Utilization Among Community-Dwelling Adults with Clinical Features of Dementia with Lewy Bodies, PI: Wyman-Chick, National Institute on Aging/NIH/DHHS

SCISIPBIO: Constructing Heterogeneous Scholarly Graphs to Examine Social Capital Accumulation During Mentored K Awardees Transition to Research Independence: Explicating a Matthew Mechanism, PI: Mabry, National Science Foundation

Hotspotting Cardiometabolic Disparities for Simulated Advances in Population Care, PI: Westgard, National Institute on Aging/NIH/DHHS

Optimizing the Value of PROMs in Improving Care Delivery through Health Information Technology (PROMOTE) , PI: Solberg, Agency for Healthcare Research and Quality

Affiliation
positions
  • Manager of Statistical Services and Biostatistician, Research Methodology Group 2019 -
  • Publications While At HealthPartners
    Highlights
    selected publications
    Journal Article
  • Cholinesterase inhibitors for patients with dementia: patterns of prescribing and disparities in treatment. 
    Journal of Alzheimer's Disease. 2026
  • Impact of envelope teaser on mail and web research survey response rates and representation. 
    BMC Medical Research Methodology. 2026
  • Impact of pediatric housing status and racial profile on outcomes after traumatic injury. 
    Journal of Pediatric Surgery. 2026
  • Is non-sac contained matrix a major predictor for residual disease in acquired cholesteatoma?. 
    Otolaryngology and Head and Neck Surgery. 2026
  • Outcomes after splenic injury in geriatric trauma: is splenic embolization helpful?. 
    The journal of trauma and acute care surgery. 2026
  • Pilot randomized trial of medical cannabis to reduce symptom burden in patients with newly diagnosed advanced pancreatic cancer (CanPan). 
    JCO Oncol Pract. 2026
  • Acupuncture treatment for chronic post-traumatic headache in individuals with mild traumatic brain injury: a pilot study. 
    Journal of Neurotrauma. 2025
  • Acupuncture treatment for individuals with myasthenia gravis - a pilot randomized clinical trial. 
    Glob Adv Integr Med Health. 2025
  • Better together? Reducing vancomycin use and acute kidney injury with a blended AUC and trough-based dosing guideline. 
    Pharmacotherapy. 2025
  • Damage control surgery in the era of globalization of health care - military and international outcomes: a systematic review. 
    Journal of Surgical Research. 2025
  • Distinguishing prodromal dementia with Lewy bodies from prodromal Alzheimer disease: a longitudinal study. 
    Neurology. Clinical practice. 2025
  • From patch to plate: evaluation of systemic symptoms in patients with positive patch test reactions to sodium disulfite. 
    Dermatitis. 2025
  • Prevalence of diabetes among U.S. refugees and opportunities to improve screening, 2012-2022. 
    Journal of immigrant and minority health. 2025
  • Sex differences in prodromal dementia with Lewy bodies using the National Alzheimer's Coordinating Center data. 
    Alzheimer's & dementia. 2025
  • Tetanus and diphtheria vaccination coverage and electronic health record alerts for immigrants and refugees at three United States health systems, 2017-2023. 
    Vaccine. 2025
  • The effect of individualized surgeon comparative feedback on arthroplasty outcomes: an interrupted time series analysis. 
    American Journal of Medical Quality. 2025
  • An electronic teen questionnaire, the eTeenQ, for risk behavior screening during adolescent well visits in an integrated health system: development and pilot implementation. 
    JMIR pediatrics and parenting. 2024
  • COVID-19 vaccine uptake among non-US-born populations in the United States, 2020-2022. 
    Vaccine. 2024
  • Colchicine and/or Naltrexone for hospitalized COVID-19 patients not requiring high levels of ventilatory support (COLTREXONE): a prospective, randomized, open-label trial. 
    Cureus. 2024
  • Identifying racial and ethnic disparities in acute inpatient rehabilitation. 
    Archives of Physical Medicine and Rehabilitation. 2024
  • Improving access to yoga for chronic pain in a Spanish-speaking community: a quality improvement initiative. 
    Pain Management Nursing. 2024
  • The impact of stimulant medications on blood pressure and body mass index in children with attention deficit hyperactivity disorder. 
    Academic Pediatrics. 2024
  • The relationship between anticholinergic burden and frailty in the year preceding a diagnosis of dementia with Lewy bodies. 
    Alzheimer's & dementia (Amsterdam, Netherlands). 2024
  • Time to COVID-19 vaccination by language and country of origin. 
    JAMA network open. 2024
  • Use of sequential hot-deck imputation for missing health care systems data for population health research. 
    Medical Care. 2024
  • Care coordination in primary care: mapping the territory. 
    American Journal of Managed Care. 2023
  • Describing racial disparity in hypertension control in a large Minnesota outpatient practice. 
    Health services research and managerial epidemiology. 2023
  • Diffusion restriction in the splenium: a comparative study of cytotoxic lesions of the corpus callosum (CLOCCs) versus lesions of vascular etiology. 
    Journal of clinical medicine. 2023
  • Diffusion-restricted lesions of the splenium: clinical presentation, radiographic patterns, and patient outcomes. 
    Neurology. Clinical practice. 2023
  • Factor analysis in distinguishing coronavirus disease 2019 from other influenza-like illness using a validated patient-reported outcome instrument FLU-PRO Plus: a prospective real-world cohort study. 
    Medical Care. 2023
  • Potentially preventable readmissions after acute inpatient rehabilitation. 
    American Journal of Physical Medicine and Rehabilitation. 2023
  • Adjusting for variation in patient-reported outcome measures is needed to improve care after total knee arthroplasty. 
    Journal of the American Academy of Orthopaedic Surgeons. 2022
  • Clinical decision support with or without shared decision making to improve preventive cancer care: a cluster-randomized trial. 
    Medical Decision Making. 2022
  • Human papillomavirus vaccination clinical decision support for young adults in an upper midwestern healthcare system: a clinic cluster-randomized control trial. 
    Human Vaccines & Immunotherapeutics. 2022
  • Improving care for patients with chronic hepatitis B via establishment of a disease registry. 
    American Journal of Tropical Medicine and Hygiene. 2022
  • Is shared decision-making associated with better patient-reported outcomes? A longitudinal study of patients undergoing total joint arthroplasty. 
    Clinical Orthopaedics and Related Research. 2022
  • Is the promise of PROMs being realized? Implementation experience in a large orthopedic practice. 
    American Journal of Medical Quality. 2022
  • Primary care clinicians' opinions before and after implementation of cancer screening and prevention clinical decision support in a clinic cluster-randomized control trial: a survey research study. 
    BMC Health Services Research. 2022
  • Rate and predictors of acute care encounters in the first month after stroke. 
    Journal of Stroke and Cerebrovascular Diseases. 2022
  • Readmission to an acute care hospital during inpatient rehabilitation after stroke. 
    American Journal of Physical Medicine and Rehabilitation. 2022
  • Systematic surveillance of patient-reported symptoms of viral respiratory tract infectious syndromes in diverse populations. 
    BMC Health Services Research. 2022
  • What do orthopaedists believe is needed for incorporating patient-reported outcome measures into clinical care? A qualitative study. 
    Clinical Orthopaedics and Related Research. 2022
  • Barriers to achieving target door-to-needle time in patients treated with IV thrombolysis. 
    Healthc Res J. 2021
  • Design and rationale of an intervention to improve cancer prevention using clinical decision support and shared decision making: a clinic-randomized trial. 
    Contemporary Clinical Trials. 2021
  • Evaluation of fixed versus variable dosing of 4-factor prothrombin complex concentrate for emergent warfarin reversal. 
    American Journal of Emergency Medicine. 2021
  • The impact of personalized clinical decision support on primary care patients' views of cancer prevention and screening: a cross-sectional survey. 
    BMC Health Services Research. 2021
  • Review
  • Should platelet transfusion be used to reverse preinjury antiplatelet agents in traumatic brain injury? A systematic review and meta-analysis [systematic review, meta-analysis]. 
    The journal of trauma and acute care surgery. 2026
  • Factors associated with increased health care utilization for patients with dementia with Lewy bodies: a narrative review [review]. 
    Journal of patient-centered research and reviews. 2024
  • Contact
    full name
  • Ella A. Chrenka, M.S.
  • primary email
  • Ella.A.Chrenka@HealthPartners.com
  • located in facility
    Quick Info
    Publications
    Publications in the past 10 years based solely on publications while at HealthPartners. Publications in prior years appear in grey.
    Collaboration
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