Mai P. Nguyen, MD
Research Investigator, Department of Orthopedic Surgery, Regions Hospital
Research Investigator

Mai Nguyen, MD is a board-certified orthopedic trauma surgeon who has dedicated her career to improving care and outcomes for trauma patients. Her work aims to optimize patient outcomes by setting up standard of care and establishing the optimum treatment for injured patients. Her research projects have won multiple awards including NIH/NIAMS funding, and she has established herself as a research leader in the local trauma network.

With over 40 peer-reviewed publications, Dr. Nguyen is nationally known for her orthopedic trauma expertise and her research works. She is an active reviewer for six peer-reviewed orthopedic journals, including the highest impact general orthopedic and orthopedic trauma journals. She was selected as a young clinician scholar for the Career Development Program in 2015 by the Orthopaedic Trauma Association, American Academy of Orthopaedic Surgeons, Orthopaedic Research and Education Foundation, and Orthopaedic Research Society, and in 2019 for the prestigious grant mentoring and career development program sponsored by the United States Bone & Joint Initiative. Her research has been consistently highlighted with posters and podium presentations at the annual Orthopaedic Trauma Association and the American Academy of Orthopaedic Surgeons meetings. In the metro Twin Cities area, Dr. Nguyen was instrumental in establishing the North Star Trauma Network which includes six trauma hospitals and 15 orthopedic trauma surgeons. She currently serves as the Research Director of the network which facilitates multi-center research across the sites.

Affiliations/other offices held: Assistant professor, Department of Orthopedic Surgery, Regions Hospital, University of Minnesota

Joined the Institute:

Education and training: MD, Vanderbilt University School of Medicine; Residency, University of Iowa Hospitals and Clinics; Fellowship, Metro Health System.

Overview/research interests: Dr. Nguyen has dedicated her career to optimizing patient-centered outcomes in the field of trauma. Her research interests include trauma recovery, implementation of patient-reported-outcome-measures in clinical practice, utilization of orthopedic implants, geriatric fragility fractures, use of innovative surgical techniques in improving outcomes of articular fractures (such as knee/ tibial plateau), care for poly-traumatized patients, and gunshot related injuries. 

  • Arthroscopic-assisted tibial plateau fixation (AATPF) vs Open reduction internal fixation (ORIF): A multicenter randomized controlled trial (R34AR082020). Source: NIAMS. 07/01/2023-06/30/2025. Role: co-PI.
  • Percutaneous Sacral Screw Fixation for Operative Treatment of Geriatric Lateral Compression 1 Pelvic Fracture- A Randomized Controlled Trial. Source: Orthopaedic Trauma Association. 06/23/2022-06/22/2024. Role: PI.
  • Management and Outcome of GSWs to Extremities (Nguyen). Source: Regions: Orthopaedic Surgery. 08/02/2022-08/31/2023. Role: PI. 
  • Comparison of Operative and Non-Operative Management of Elderly Fragility Pelvic Ring Fractures (Nguyen). Source: Regions: Orthopaedic Surgery. 09/20/2022-09/19/2023. Role: PI.
  • Comparison of Hardware Removal and Complication Rates between Mini and Small Fragment Implants for Lateral Malleolar Fixation. Source: Regions: Orthopaedic Surgery. 11/20/2022-11/21/2024. Role: PI. 
  • Review of Postoperative Care for Geriatric Hip Fracture Patients (Nguyen). Source: Regions: Orthopaedic Surgery. 08/06/2020-09/09/2021. Role: PI.
  • Research Investigator, Orthopedic trauma
  • Publications While At HealthPartners
    selected publications
    Journal Article
  • Ankle fractures: high implant cost is not associated with better patient reported outcomes
    Injury. 2023
  • Comparison of clinical and radiographic outcomes of arthroscopic-assisted percutaneous fixation versus open reduction internal fixation of lateral tibial plateau fractures
    International Orthopaedics. 2023
  • Arthroscopically assisted percutaneous screw fixation of tibial plateau fractures
    JBJS essential surgical techniques. 2022
  • Association of preoperative opioid use with postoperative opioid use and patient-reported outcomes in ankle fracture fixation patients
    Foot Ankle Orthop. 2022
  • Capturing patient-reported outcomes: paper versus electronic survey administration
    OTA Int. 2022
  • Comparison of the Neer classification to the 2018 update of the Orthopedic Trauma Association/AO fracture classification for classifying proximal humerus fractures
    OTA Int. 2022
  • Usage of orthopaedic trauma registries among members of the International Orthopaedic Trauma Association: how are we doing?
    OTA Int. 2022
  • Costs of care for low-energy extremity gunshot injuries are reduced with standardized treatment
    Journal of Orthopaedic Trauma. 2021
  • Implementation of a multidisciplinary "code hip" protocol is associated with decreased time to surgery and improved patient outcomes
    Geriatric orthopaedic surgery & rehabilitation. 2021
  • Management of civilian low-velocity gunshot injuries to an extremity
    Journal of Bone and Joint Surgery (American Volume). 2021
  • Minimizing nonessential follow-up for hip fracture patients
    Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews. 2021
  • Walking greater than 5 feet after hip fracture surgery is associated with fewer complications, including death
    Journal of the American Academy of Orthopaedic Surgeons. 2021
  • Alleviation of pain after femur and tibia shaft fractures using nothing stronger than codeine and tramadol
    Journal of Orthopaedic Trauma. 2020
  • Impact of the fascia iliaca block on pain, opioid consumption, and ambulation for patients with hip fractures: a prospective, randomized study
    Journal of Orthopaedic Trauma. 2020
  • Implementation of a mobile app for trauma education: results from a multicenter study
    Trauma surgery & acute care open. 2020
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