Kristin Palmsten, ScD
Senior Research Investigator
"My work helps pregnant patients make decisions about medicines and vaccines."
About

Kristin Palmsten, ScD, is a Senior Research Investigator, Co-Director of the Pregnancy and Child Health Research Center, and Research and Scientific Mentor at HealthPartners Institute. Dr. Palmsten is a perinatal epidemiologist and pharmacoepidemiologist. She received her doctorate in Epidemiology from the Harvard T.H. Chan School of Public Health and completed a postdoctoral fellowship in the Department of Pediatrics at the University of California San Diego. She received an Abraham Lilienfeld Student Prize from the Society for Epidemiologic Research and an Early Career Professional Achievement Award from The National Maternal and Child Health Epidemiology Awards.

Dr. Palmsten’s research has primarily focused on using big data to study perinatal health, including drug safety during pregnancy, and epidemiologic methods to reduce bias in studies of exposures during pregnancy. Currently, she is the principal investigator of two multi-site studies funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The MOM Study assesses the effects of antidepressants or psychotherapy initiation during pregnancy on infant outcomes and breastfeeding (R01HD100579). The CALM Study assesses the association between antenatal and postpartum COVID-19 vaccination and lactation and infant outcomes (R01HD107753). Dr. Palmsten welcomes the opportunity to build research collaborations within HealthPartners and with external partners.  

Joined the Institute:
 2017

Education and training: ScD, Epidemiology, Harvard School of Public Health (now Harvard T.H. Chan School of Public Health); MS, Epidemiology, Harvard School of Public Health; BS, Boston College.

Overview/research interests: Perinatal epidemiology, pharmacoepidemiology, epidemiologic methods, medication use and safety during pregnancy and lactation.

Current research activities and funding: 

  • Tdap Vaccination during Pregnancy or Postpartum and Lactation-Related Outcomes
  • Maternal COVID-19 Vaccination and Lactation Outcomes (CALM study)
  • Managing Our Mood (MOM) Study: Treatment Initiation for New Episodes of Depression in Pregnant Women
  • Mental Health Research Network III-Digital Mindfulness Based Cognitive Therapy for Perinatal Depression
  • Maternal Obesity, Milk Composition, and Infant Growth (MILK II)
  • Maternal Health Care Utilization and Morbidity: The First 24 months
  • Birth Defects Study To Evaluate Pregnancy exposures (BD-STEPS) II
  • Vaccine Safety Datalink
  • Innovation in Medical Evidence and Development Surveillance (IMEDS)
  • Distributed Research Network
Affiliation
positions
  • Senior Research Investigator, Pregnancy and child health 2017 -
  • Research Investigator, Pregnancy and child health 2017 - 2021
  • Publications While At HealthPartners
    Highlights
    selected publications
    Journal Article
  • COVID-19 vaccination in pregnancy and postpartum and human milk feeding non-initiation and discontinuation. 
    American Journal of Epidemiology. 2026
  • Characteristics and incidence of lactational mastitis using state-wide data from 2016 to 2022. 
    Journal of women's health (2002). 2026
  • Comparison of lactation information from electronic health records with survey data across five US health systems. 
    Epidemiology (Cambridge, Mass.). 2026
  • Gestational diabetes, human milk oligosaccharide (HMO) concentrations, and their links to infant weight gain and the gut microbiome in a United States observational cohort. 
    American Journal of Clinical Nutrition. 2026
  • Interim safety of RSVpreF vaccination during pregnancy. 
    JAMA. 2026
  • Language and racial disparities in COVID-19 vaccination during pregnancy and lactation. 
    Vaccine. 2026
  • Linkage of electronic health record data across two healthcare systems for perinatal health research: a privacy-preserving approach. 
    Paediatric and Perinatal Epidemiology. 2026
  • Maternal intellectual and developmental disabilities and infant outcomes. 
    JAMA network open. 2026
  • Opportunities and challenges to leveraging real-world data for post-market safety studies in pregnancy and lactation: meeting proceedings. 
    Journal of women's health (2002). 2026
  • Provider perspectives to inform a patient-facing decision aid on oral corticosteroid use during pregnancy and evaluation of the aid. 
    Pharmacoepidemiology and Drug Safety. 2026
  • Sequential safety surveillance of RSVpreF vaccination during pregnancy early in the postapproval period. 
    JAMA network open. 2026
  • Severe maternal morbidity and hypertensive disorders of pregnancy among women with intellectual disabilities: identifying potential intervention targets. 
    American journal of obstetrics & gynecology MFM. 2026
  • Ambulatory care utilization in the first 24 months' postpartum by rurality and pregnancy-related conditions: a prospective cohort study from Maine. 
    Journal of Rural Health. 2025
  • Comparison of linked EHR-pharmacy data and administrative claims data: medication fills during pregnancy. 
    Pharmacoepidemiology and Drug Safety. 2025
  • Effectiveness and safety of the recombinant zoster vaccine in adult patients with systemic lupus erythematosus: a claims-based retrospective cohort study in the USA. 
    RMD open. 2025
  • Prevalence of GLP-1 medication exposure prior to, during, and after pregnancy using state-wide data from 2017 to 2023. 
    American journal of obstetrics & gynecology MFM. 2025
  • Primary and secondary adherence to antihypertensive medications during pregnancy and postpartum. 
    Pregnancy Hypertension. 2025
  • Validation of lactational mastitis diagnosis codes in electronic health care data. 
    Epidemiology (Cambridge, Mass.). 2025
  • Acute health care utilization in the first 24 months postpartum by rurality and pregnancy complications: a prospective cohort study. 
    Health Services Research. 2024
  • Association between gestational diabetes and cardiovascular disease within 24 months postpartum. 
    American journal of obstetrics & gynecology MFM. 2024
  • Characterisation and validation of lactation information from structured electronic health records for use in pharmacoepidemiological studies. 
    Paediatric and Perinatal Epidemiology. 2024
  • Does reversible postpartum contraception reduce the risk of pregnancy condition recurrence? A longitudinal claims-based study from Maine. 
    Annals of Epidemiology. 2024
  • Association between hypertensive disorders of pregnancy and cardiovascular diseases within 24 months after delivery. 
    American Journal of Obstetrics and Gynecology. 2023
  • Association of prenatal depression with new cardiovascular disease within 24 months postpartum. 
    Journal of the American Heart Association. 2023
  • Influenza vaccination during pregnancy and risk of selected major structural congenital heart defects, National Birth Defects Prevention Study 2006-2011. 
    Birth defects research. 2023
  • Maternal hepatitis C prevalence and trends by county, US: 2016-2020. 
    Paediatric and Perinatal Epidemiology. 2023
  • Mental health within 24 months after delivery among women with common pregnancy conditions. 
    Journal of women's health (2002). 2023
  • Patterns in prescription opioids, benzodiazepines, and stimulants filled by pregnant Medicaid beneficiaries. 
    JAMA pediatrics. 2023
  • Provision of postpartum contraception before and after the start of the COVID-19 pandemic in Maine. 
    Public Health Reports. 2023
  • Rural-urban residence and sequelae of hypertensive disorders of pregnancy in the first year postpartum, 2007 - 2019. 
    Pregnancy Hypertension. 2023
  • Special issue: big data in perinatal epidemiology methodologic considerations. 
    Paediatric and Perinatal Epidemiology. 2023
  • The most common medications dispensed to lactating persons: an electronic health record-based approach. 
    Pharmacoepidemiology and Drug Safety. 2023
  • Antidepressant fill and dose trajectories in pregnant women with depression and/or anxiety: a Norwegian registry linkage study. 
    Clinical Epidemiology. 2022
  • Differences in the association between oral glucocorticoids and risk of preterm birth by data source: reconciling the results. 
    Arthritis Care & Research. 2022
  • Influenza vaccination during pregnancy and risk of selected major structural noncardiac birth defects, National Birth Defects Prevention Study 2006-2011. 
    Pharmacoepidemiology and Drug Safety. 2022
  • Point: uncertainty about estimating the risks of COVID-19 during pregnancy. 
    Paediatric and Perinatal Epidemiology. 2022
  • Safety of live-attenuated vaccines in children exposed to biologic response modifiers in utero. 
    Pediatrics. 2022
  • "I know my body better than you:" patient focus groups to inform a decision aid on oral corticosteroid use during pregnancy. 
    Pharmacoepidemiology and Drug Safety. 2021
  • Evidence of under-reporting of early-onset preeclampsia using register data. 
    Paediatric and Perinatal Epidemiology. 2021
  • Oral corticosteroids and risk of preterm birth in the California Medicaid program. 
    The journal of allergy and clinical immunology. In practice. 2021
  • Rural-urban residence and maternal hepatitis C infection, US: 2010-2018. 
    American Journal of Preventive Medicine. 2021
  • Acetaminophen use in pregnancy: examining prevalence, timing, and indication of use in a prospective birth cohort. 
    Paediatric and Perinatal Epidemiology. 2020
  • Asthma prevalence among women aged 18 to 44 in the United States: National Health and Nutrition Examination Survey 2001-2016. 
    Journal of Asthma. 2020
  • Oral corticosteroid use during pregnancy and risk of preterm birth. 
    Rheumatology (Oxford, England). 2020
  • Patterns of prenatal antidepressant exposure and risk of preeclampsia and postpartum haemorrhage. 
    Paediatric and Perinatal Epidemiology. 2020
  • Prenatal antidepressant use and risk of adverse neonatal outcomes. 
    Pediatrics. 2020
  • Using nationally representative survey data for external adjustment of unmeasured confounders: an example using the NHANES data. 
    Pharmacoepidemiology and Drug Safety. 2020
  • Validation of mother-infant linkage using Medicaid Case ID variable within the Medicaid Analytic eXtract (MAX) database. 
    Pharmacoepidemiology and Drug Safety. 2019
  • Agreement between maternal report and medical records during pregnancy: medications for rheumatoid arthritis and asthma. 
    Paediatric and Perinatal Epidemiology. 2018
  • In vitro fertilization, interpregnancy interval, and risk of adverse perinatal outcomes. 
    Fertility and Sterility. 2018
  • Longitudinal trajectories of antidepressant use in pregnancy and the postnatal period
    2018
  • Most frequently reported prescription medications and supplements in couples planning pregnancy: The LIFE Study. 
    Reproductive Sciences. 2018
  • Patterns of prednisone use during pregnancy in women with rheumatoid arthritis: daily and cumulative dose. 
    Pharmacoepidemiology and Drug Safety. 2018
  • Revisiting the Table 2 fallacy: a motivating example examining preeclampsia and preterm birth. 
    Paediatric and Perinatal Epidemiology. 2018
  • Subclinical and clinical chorioamnionitis, fetal vasculitis, and risk for preterm birth: a cohort study. 
    Placenta. 2018
  • Early-onset preeclampsia in lupus pregnancy. 
    Paediatric and Perinatal Epidemiology. 2017
  • Medication use among pregnant women with systemic lupus erythematosus and general population comparators. 
    Rheumatology (Oxford, England). 2017
  • Constructing causal diagrams for common perinatal outcomes: benefits, limitations and motivating examples with maternal antidepressant use in pregnancy. 
    Paediatric and Perinatal Epidemiology. 2016
  • What to expect when expecting with systemic lupus erythematosus (SLE): a population-based study of maternal and fetal outcomes in SLE and Pre-SLE. 
    Arthritis Care & Research. 2016
  • Editorial Article
  • The data giveth, but what do we take away [editorial]?. 
    Paediatric and Perinatal Epidemiology.  37. 2023
  • Making the best use of data not created for research [editorial]. 
    Paediatric and Perinatal Epidemiology.  32. 2018
  • Review
  • Longitudinal methods for modeling exposures in pharmacoepidemiologic studies in pregnancy [review]. 
    Epidemiologic Reviews. 2022
  • A review of systemic corticosteroid use in pregnancy and the risk of select pregnancy and birth outcomes [review]. 
    Rheumatic Diseases Clinics of North America. 2017
  • Audio Document
  • HealthPartners study investigates depression treatment during pregnancy [interview]. 
    MinnPost. 2021
  • Contact
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  • Kristin Palmsten, ScD
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    Publications in the past 10 years based solely on publications while at HealthPartners. Publications in prior years appear in grey.
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