Kristin L. Popp, PhD, MS
TRIA Research and Education Center Investigator
"My research is fueled by a commitment to empower active women – whether in pursuit of their performance and lifestyle goals or recovering from a bone stress injury – by gaining greater understanding of factors that lead to poor bone health and developing innovative strategies that optimize recovery, prevent future injuries, and safeguard their long-term bone health."
About

Dr. Kristin Popp is a Research Investigator at the HealthPartners Institute TRIA Research and Education Center. She holds an academic affiliation with Boston Children’s Hospital as the Associate Director of Research for the Wu Tsai Alliance Female Athlete Program. Dr. Popp’s research is centered on bone stress injuries (i.e. stress reactions and stress fractures) among athletes and military personnel, with a particular focus on the structural, strength and microarchitectural aspects of bone and the risk factors that compromise these parameters. Her work is distinguished by the integration of bone metabolism markers, advanced imaging techniques, reproductive health, and innovative strategies for improving rehabilitation to optimize recovery, prevent future injuries, and improve long-term bone health.

Dr. Popp is widely published and has presented her research both nationally and internationally, contributing to the field of bone health and injury prevention. In addition to her current roles, she also serves as a Senior Sports Scientist at Orreco in Galway, Ireland, where she collaborates with professional sports teams on biomarker data analysis to enhance athletic performance. Her academic background includes a PhD in Exercise Physiology form the University of Minnesota where she focused on bone geometry and strength in athletes with a history of bone stress injuries, as well as a postdoctoral fellowship at Massachusetts General Hospital in Boston, MA. Dr. Popp spent five years as a Scientist for Oak Ridge Institute for Science and Education at the U.S. Army Research Institute of Environmental Medicine (USARIEM).

Joined the Institute: 2021

Education and training: Postdoctoral Fellow, Harvard Medical School/Massachusetts General Hospital; PhD, Kinesiology, University of Minnesota; MA, Kinesiology, University of Minnesota; BA, Exercise Science, Valparaiso University.

Affiliations/other offices held: Associate Director of Research, Wu Tsai Human Performance Alliance Female Athlete Program, Boston Children's Hospital; Senior Sports Scientist, Orreco, Galway, Ireland.

Overview/research interests: Understanding and mitigating risk factors that compromise bone structure and strength to optimizing bone health and preventing bone stress injuries in active populations, including athletes and military personnel. I aim to develop effective bone stress injury prevention and rehabilitation strategies, helping individuals achieve their long-term lifestyle and performance goals and prevent future injuries, including additional bone stress injuries and fragility fractures later in life.

Current research activities and funding:

TRIA Research and Education Center
Identifying Risk of Multiple Bone Stress Injuries: Implications for Future Interventions
Role: PI. (2023-2025)

TRIA Research and Education Center
Assessing Agreement in Bone Stress Injury Severity, Utilizing Three Unique Magnetic Resonance Imaging Grading Scales
Role: PI. (2024-2025)

Clara and Joe Tai Foundation
Wu Tsai Female Athlete Program at Boston Children’s Hospital (2022-2026)
1.Bone Stress Injury Multi-Center Natural History Study: Assess lower extremity bone stress injury healing and recovery to identify factors affecting recovery variability.
Role: PI. 50% effort 2023-2026

Congressionally Directed Medical Research Program; Peer Reviewed Orthopaedic Research Program. U.S. Research Institute of Environmental Medicine (2020-2023)
Exoskeletons for rapid return to duty after tibial stress fracture.
Role: Co-I. 5% effort 2021-2025

Affiliation
positions
  • Institute Research Investigator, TRIA Research and Education Center
  • Publications While At HealthPartners
    Highlights
    selected publications
    Journal Article
  • Bone Health and Body Composition of Postmenopausal Exercisers and Sedentary Controls. 
    International Journal of Sports Medicine. 2026
  • Bone stress injury recovery and return to sport in runners: a multi-site prospective observational cohort study protocol across the USA and Canada. 
    BMJ open. 2026
  • Circulating sex hormones, specifically estrogen in females and testosterone in males, are associated with ambient environmental temperature during prolonged physical training. 
    Temperature (Austin, Tex.). 2026
  • Inflammation and alterations in redox homeostasis precede and persist following musculoskeletal injury in US army trainees. 
    British Journal of Sports Medicine. 2026
  • Biomechanics associated with bone stress injury in athletes differ by proximal and distal anatomical locations: a cross-sectional analysis. 
    BMJ open sport & exercise medicine. 2025
  • Bone status of female elite warfighters: a retrospective comparative analysis to basic combat trainees. 
    BMJ Mil Health. 2025
  • Infographic. Translating the international Delphi consensus on bone stress injuries into clinical practice. 
    British Journal of Sports Medicine. 2025
  • International Delphi consensus on bone stress injuries in athletes. 
    British Journal of Sports Medicine. 2025
  • Model for musculoskeletal injury risk factors among US Army basic combat trainees. 
    JAMA network open. 2025
  • Association between changes in serum bone metabolism markers and bone microarchitecture changes during basic combat training - the ARMI study. 
    Bone. 2024
  • Factors associated with high-risk and low-risk bone stress injury in female runners: implications for risk factor stratification and management. 
    Orthopaedic journal of sports medicine. 2024
  • Hypothalamic-pituitary-ovarian axis suppression is common among women during US Army Basic Combat Training. 
    British Journal of Sports Medicine. 2024
  • Changes in distal tibial microarchitecture during eight weeks of U.S. Army basic combat training differ by sex and race. 
    JBMR plus. 2023
  • Impact loading in female runners with single and multiple bone stress injuries during fresh and exerted conditions. 
    Journal of sport and health science. 2023
  • Male runners with lower energy availability have impaired skeletal integrity compared to nonathletes. 
    Journal of Clinical Endocrinology and Metabolism. 2023
  • Physiology of health and performance: enabling success of women in combat arms roles. 
    Military Medicine. 2023
  • The risk of menstrual dysfunction increases for women during U.S. Army basic combat training. 
    Medicine and Science in Sports and Exercise. 2023
  • Low energy availability surrogates associated with lower bone mineral density and bone stress injury site. 
    PM & R. 2022
  • Restrictive eating and prior low-energy fractures are associated with history of multiple bone stress injuries. 
    International Journal of Sport Nutrition and Exercise Metabolism. 2022
  • Serum 25-hydroxyvitamin D is associated with bone microarchitecture and strength in a multiracial cohort of young adults. 
    Journal of Clinical Endocrinology and Metabolism. 2022
  • Changes in volumetric bone mineral density over 12 months after a tibial bone stress injury diagnosis: implications for return to sports and military duty. 
    American Journal of Sports Medicine. 2021
  • Physical activity, menstrual history, and bone microarchitecture in female athletes with multiple bone stress injuries. 
    Medicine and Science in Sports and Exercise. 2021
  • Editorial Article
  • Rocket science: what spaceflight can tell us about skeletal health on earth [editorial]. 
    British Journal of Sports Medicine.  55. 2021
  • Review
  • Exercise for optimizing bone health after hormone-induced increases in bone stiffness [review]. 
    Frontiers in Endocrinology. 2023
  • Return to sport following low-risk and high-risk bone stress injuries: a systematic review and meta-analysis [meta-analysis, systematic review]. 
    British Journal of Sports Medicine. 2023
  • Bone stress injuries [review]. 
    Nature reviews. Disease primers. 2022
  • Impact of low energy availability on skeletal health in physically active adults [review]. 
    Calcified Tissue International. 2022
  • Unraveling the physiologic paradoxes that underlie exercise prescription for stress fracture prevention [review]. 
    Experimental Biology and Medicine (Maywood, N.J.). 2022
  • Grand Rounds
  • TRIA Orthopedics Grand Rounds - Sex Hormone Suppression in Active Young Women: Implications for Bone Health
    2023
  • Contact
    full name
  • Kristin L. Popp, PhD, MS
  • primary email
  • Kristin.popp@tria.com
  • located in facility
    Quick Info
    Publications
    Publications in the past 10 years based solely on publications while at HealthPartners. Publications in prior years appear in grey.
    Collaboration
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