About

Publications

selected publications

Journal Article

Biological principles of stereotactic body radiation therapy (SBRT) and stereotactic radiation surgery (SRS): indirect cell death. 

International Journal of Radiation Oncology, Biology, Physics. 2021

Quality of life and adverse events: prognostic relationships in long-term ovarian cancer survival. 

Journal of the National Cancer Institute. 2021

Beyond an updated graded prognostic assessment (Breast GPA): a prognostic index and trends in treatment and survival in breast cancer brain metastases from 1985 to today. 

International Journal of Radiation Oncology, Biology, Physics. 2020

Development of a disease-specific graded prognostic assessment index for the management of sarcoma patients with brain metastases (Sarcoma-GPA). 

BMC cancer. 2020

Estrogen/progesterone receptor and HER2 discordance between primary tumor and brain metastases in breast cancer and its effect on treatment and survival. 

Neuro-Oncology. 2020

Survival in patients with brain metastases: summary report on the updated diagnosis-specific graded prognostic assessment and definition of the eligibility quotient. 

Journal of Clinical Oncology. 2020

Estimating survival in patients with gastrointestinal cancers and brain metastases: an update of the graded prognostic assessment for gastrointestinal cancers (GI-GPA)

2019

GOG 8020/210: Risk stratification of lymph node metastasis, disease progression and survival using single nucleotide polymorphisms in endometrial cancer: an NRG oncology/gynecologic oncology group study. 

Gynecologic Oncology. 2019

Safety and efficacy of a five-fraction stereotactic body radiotherapy schedule for centrally located non-small-cell lung cancer: NRG Oncology/RTOG 0813 Trial. 

Journal of Clinical Oncology. 2019

Survival and prognostic factors in patients with gastrointestinal cancers and brain metastases: have we made progress?. 

Translational Research: The Journal of Laboratory and Clinical Medicine. 2019

Brain metastases in lung cancer with targetable mutations-reply. 

JAMA oncology. 2018

Cumulative doses to brain and other critical structures after multisession gamma knife stereotactic radiosurgery for treatment of multiple metastatic tumors. 

Frontiers in Oncology. 2018

Effect of targeted therapies on prognostic factors, patterns of care, and survival in patients with renal cell carcinoma and brain metastases. 

International Journal of Radiation Oncology, Biology, Physics. 2018

Estimating survival for renal cell carcinoma patients with brain metastases: an update of the Renal Graded Prognostic Assessment tool. 

Neuro-Oncology. 2018

Prognostic models for patients with brain metastases after stereotactic radiosurgery with or without whole brain radiotherapy: a validation study. 

Journal of Neuro-Oncology. 2018

Adjuvant radiation therapy, androgen deprivation, and docetaxel for high-risk prostate cancer postprostatectomy: Results of NRG Oncology/RTOG study 0621. 

Cancer. 2017

Case report of extended survival and quality of life in a melanoma patient with multiple brain metastases and review of literature. 

Cureus. 2017

Effect of gamma knife radiosurgery and programmed cell death 1 receptor antagonists on metastatic melanoma. 

Cureus. 2017

Estimating survival in melanoma patients with brain metastases: an update of the graded prognostic assessment for melanoma using molecular markers (melanoma-molGPA). 

International Journal of Radiation Oncology, Biology, Physics. 2017

Estimating survival in patients with lung cancer and brain metastases: an update of the graded prognostic assessment for lung cancer using molecular markers (lung-molGPA). 

JAMA oncology. 2017

Significance of co-expression of epidermal growth factor receptor and Ki67 on clinical outcome in patients with anal cancer treated with chemoradiotherapy: an analysis of NRG Oncology RTOG 9811. 

International Journal of Radiation Oncology, Biology, Physics. 2017

The prognostic value of BRAF, C-KIT, and NRAS mutations in melanoma patients with brain metastases. 

International Journal of Radiation Oncology, Biology, Physics. 2017

Integrating bevacizumab and radiation treatment of brain metastasis: is there sense and sensibility in this approach?. 

Annals of translational medicine. 2016

The effect of gene alterations and tyrosine kinase inhibition on survival and cause of death in patients with adenocarcinoma of the lung and brain metastases. 

International Journal of Radiation Oncology, Biology, Physics. 2016

Indirect tumor cell death after high-dose hypofractionated irradiation: implications for stereotactic body radiation therapy and stereotactic radiation surgery. 

International Journal of Radiation Oncology, Biology, Physics. 2015

A review of stereotactic radiosurgery in the management of brain metastases. 

Technology in Cancer Research & Treatment. 2003

Editorial Article

The past, current and future management of brain metastases in EGFR-mutant non-small cell lung cancer [editorial]. 

Neuro-Oncology.  23. 2021

Omitting radiosurgery in melanoma brain metastases: a drastic and dangerous de-escalation [editorial]. 

Lancet Oncology.  19. 2018

Review

Current multidisciplinary management of brain metastases [review]. 

Cancer. 2020

Indirect cell death and the LQ model in SBRT and SRS [review]. 

Journal of radiosurgery and SBRT. 2020

Contact

full name

P. W. Sperduto

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Map of science