Risk of immune hemolytic anemia in children following immunization Journal Article uri icon
  • Several case reports have described immune hemolytic anemia (IHA) following vaccination in children. We examined the risk of IHA in the 42 days following vaccination exposure using a self-controlled case series study design. In our population-based cohort of nearly 4.5 million children in the Vaccine Safety Datalink, we identified 55 confirmed cases of new-onset IHA from 1991 through 2000. We found no association between IHA and diphtheria-pertussis-tetanus vaccination (incidence rate ratio (IRR)=0.65, 95% CI: 0.19-2.24), hepatitis B vaccination (IRR=1.73, 95% CI: 0.59-5.01), or any vaccination (IRR=1.04, 95% CI: 0.46-2.32).

  • Link to Article
    publication date
  • 2009
  • published in
  • Vaccine  Journal
  • Research
  • Adverse Effects
  • Cohort Studies
  • Diphtheria-Tetanus-Pertussis Vaccines
  • Hepatitis B Vaccines
  • Pediatrics
  • Vaccination
  • Additional Document Info
  • 27
  • issue
  • 52