A life-threatening flecainide overdose treated with intravenous fat emulsion Journal Article uri icon
  • Flecainide is a Vaughan Williams Class Ic antidysrhythmic associated with PR, QRS, and QTc prolongation on the electrocardiogram and development of life-threatening cardiac toxicity in overdose. The cornerstone of treatment is fluid resuscitation and the administration of magnesium and sodium bicarbonate. We report a case of flecainide overdose associated with life-threatening hemodynamic compromise successfully treated with intravenous fat emulsion (IFE) therapy. IFE should be considered as a novel adjunctive therapy in patients with life-threatening toxicity following flecainide overdose.

  • Link to Article
    publication date
  • 2013
  • published in
  • Drugs and Drug Therapy
  • Emergency Medicine
  • Heart
  • Poisoning
  • Additional Document Info
  • 36
  • issue
  • 3