Stellpflug, Samuel J., MD
Physician Emergency Medicine, JS Emergency Medicine GHI

Specialty: Director, Twin Cities Medical Toxicology Fellowship

Faculty Appointment: Associate Professor of Emergency Medicine, University of Minnesota Medical School

Publications
Teaching
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selected publications

Journal Article
- Delayed peaks of acetaminophen in overdose patients with concomitant abdominal trauma. Clinical Toxicology (Philadelphia, Pa.). 2021
- Intravenous fat emulsion does not significantly alter clotting markers in dabigatran-treated blood. Indian Journal of Hematology & Blood Transfusion. 2021
- Development and feasibility of a porcine model of amlodipine toxicity. Journal of Medical Toxicology. 2020
- Effect of methylene blue on a porcine model of amlodipine toxicity. Journal of Medical Toxicology. 2020
- Oral nitroglycerin solution for oesophageal food impaction: a prospective single-arm pilot study. Emergency Medicine Journal. 2020
- The safety of sportive chokes: a cross-sectional survey-based study. Physician and Sportsmedicine. 2020
- Urine drug screens in the emergency department: the best test may be no test at all. Journal of Emergency Nursing. 2020
- Use of a porcine model to evaluate the risks and benefits of vasopressors in propranolol poisoning. Journal of Medical Toxicology. 2020
- A comparison of resource utilization in the management of anticholinergic delirium between physostigmine and nonantidote therapy. Annals of Pharmacotherapy. 2019
- A randomized controlled study comparing high-dose insulin to vasopressors or combination therapy in a porcine model of refractory propranolol-induced cardiogenic shock. Clinical Toxicology (Philadelphia, Pa.). 2019
- A swine model of severe propranolol toxicity permitting direct measurement of brain tissue oxygenation. Journal of Medical Toxicology. 2019
- Ten years of robotripping: evidence of tolerance to dextromethorphan hydrobromide in a long-term user. Journal of Medical Toxicology. 2019
- Toxicology education in emergency medicine: an assessment and pilot study. Toxicology communications. 2019
- Hemodialysis in metformin-associated lactic acidosis due to acute overdose in a metformin-naive patient. American Journal of Emergency Medicine. 2018
- Hypoglycemia and lactic acidosis outperform King's College criteria for predicting death or transplant in acetaminophen toxic patients. Clinical Toxicology (Philadelphia, Pa.). 2018
- Oral nitroglycerin solution may be effective for esophageal food impaction. Journal of Emergency Medicine. 2018
- The hepatoprotective effects of N-acetylcysteine with repeated toxic acetaminophen ingestions: a case report. Toxicology communications. 2018
- The treatment of maternal and fetal anticholinergic toxicity with physostigmine. Toxicology communications. 2018
- A 15-year retrospective review of brake fluid exposures in children from a single poison center. Toxicology communications. 2017
- A case of U-47700 overdose with laboratory confirmation and metabolite identification. Clinical Toxicology (Philadelphia, Pa.). 2017
- Estimating the impact of adopting the revised United Kingdom acetaminophen treatment nomogram in the U.S. population. Clinical Toxicology (Philadelphia, Pa.). 2017
- A prospective study of ketamine versus haloperidol for severe prehospital agitation. Clinical Toxicology (Philadelphia, Pa.). 2016
- Refractory hypotension and "ventricular fibrillation" with large U waves after overdose. JAMA internal medicine. 2016
- The association between ketamine given for prehospital chemical restraint with intubation and hospital admission. American Journal of Emergency Medicine. 2015
- 2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe): clinical case with unique confirmatory testing. Journal of Medical Toxicology. 2014
- Asystole immediately following intravenous fat emulsion for overdose. Journal of Medical Toxicology. 2014
- The poison pen: how confident are we about iocane?. Journal of Medical Toxicology. 2014
- A blinded, randomized, controlled trial of three doses of high-dose insulin in poison-induced cardiogenic shock. Clinical Toxicology (Philadelphia, Pa.). 2013
- A life-threatening flecainide overdose treated with intravenous fat emulsion. Pacing and Clinical Electrophysiology. 2013
- Hydroxocobalamin hinders hemodialysis. American Journal of Kidney Diseases. 2013
- Bath salts: the ivory wave of trouble. Western Journal of Emergency Medicine. 2012
- Holiday plants with toxic misconceptions. Western Journal of Emergency Medicine. 2012
- Massive atropine eye drop ingestion treated with high-dose physostigmine to avoid intubation. Western Journal of Emergency Medicine. 2012
- Response to "the first published case of a pediatric diphenhydramine overdose whose electrocardiogram shows terminal 40-millisecond frontal plane QRS axis deviation". Pediatric Emergency Care. 2012
- Reversal of quetiapine-induced altered mental status with physostigmine: a case series. American Journal of Emergency Medicine. 2012
- Cardiotoxic overdose treated with intravenous fat emulsion and high-dose insulin in the setting of hypertrophic cardiomyopathy. Journal of Medical Toxicology. 2011
- High-dose insulin: a consecutive case series in toxin-induced cardiogenic shock. Clinical Toxicology (Philadelphia, Pa.). 2011
- Transaminitis: the lab test that has inflammation. Journal of Medical Toxicology. 2011
- Unique configuration of the four-lumen oesophagogastric tamponade tube (Minnesota tube) for the control of massive upper GI bleeding. Emergency Medicine Journal. 2011
- What toxicity may result from the xenobiotic responsible for the finding on this plain film? Answer: reduced iron, found in heating pads and instant hand warmers, may result in elevated serum iron concentrations and subsequent iron toxicity. Journal of Medical Toxicology. 2011
- Wide complex tachycardia in a pediatric diphenhydramine overdose treated with sodium bicarbonate. Pediatric Emergency Care. 2011
- "I Shouldn't Have Had Dessert..." A Moonflower Seed Ingestion. Western Journal of Emergency Medicine. 2010
- Addition of phenylephrine to high-dose insulin in dihydropyridine overdose does not improve outcome. Clinical Toxicology (Philadelphia, Pa.). 2010
- Intentional overdose with cardiac arrest treated with intravenous fat emulsion and high-dose insulin. Clinical Toxicology (Philadelphia, Pa.). 2010
- Which xenobiotic(s) could be responsible for the radiologic findings below? Answer: any proconvulsant xenobiotic, in this case tramadol, bupropion, and nortriptyline. Journal of Medical Toxicology. 2010
- What signs and symptoms would be expected after ingestion of this plant?. Journal of Medical Toxicology. 2009
Editorial Article
- Chokes in mixed martial arts [editorial]. Brain Injury. 33. 2019
- No established link between repeated transient chokes and chronic traumatic encephalopathy related effects [editorial]. International Journal of Environmental Research and Public Health. 16. 2019
- Critical care management of verapamil and diltiazem overdose with a focus on vasopressors: a 25-year experience at a single center [editorial]. Annals of Emergency Medicine. 63. 2014
Chapter
- Antidotes in depth: high dose insulin (HDI). Goldfrank's toxicologic emergencies. 2019
- Antidiabetic agents. Critical care toxicology: diagnosis and management of the critically poisoned patient. 2016
- Patellar tendon rupture. Atlas of clinical emergency medicine. 2016
- Antidotes in depth: high dose insulin euglycemia. Goldfrank's toxicologic emergencies. 2015
- Barbiturates. Harwood-Nuss Clinical practice of emergency medicine. 2014
- Benzodiazepines. Harwood-Nuss Clinical practice of emergency medicine. 2014
- Muscle relaxants and other sedative hypnotic agents. Harwood-Nuss Clinical practice of emergency medicine. 2014
- Beta blockers. Poisonings with cardiotoxicants: epidemiology, features, management, and exceptional therapies. 2013
- Suspected intoxication and overdose. Principles and practice of hospital medicine. 2012
Conference Paper
- Ankle pain and dystrophic calcification. Clinical photo competition (peer-reviewed) [display] 2013
Conference Poster
Review
- There is more to the mechanism of unconsciousness from vascular neck restraint than simply carotid compression [review]. International Journal of Neuroscience. 2020
- Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning [review, systematic review]. Clinical Toxicology (Philadelphia, Pa.). 2016
- Systematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity [meta-analysis, review, systematic review]. Clinical Toxicology (Philadelphia, Pa.). 2016
- What can a urine drug screening immunoassay really tell us [review]?. Journal of Pharmacy Practice. 2016
- Methodology for AACT evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning [review]. Clinical Toxicology (Philadelphia, Pa.). 2015
- 2C or not 2C: phenethylamine designer drug review [review]. Journal of Medical Toxicology. 2013
Abstract
- The undifferentiated becomes obvious: the perfect timeline [abstract]. Journal of Medical Toxicology. 2018
- Effect of methylene blue on mortality in a porcine model of amlodipine toxicity [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2017
- EMF development of a porcine model of amlodipine toxicity [abstract]. Annals of Emergency Medicine. 2016
- A prospective study of ketamine versus haloperidol for severe prehospital agitaiton [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2015
- Brom(ism)ance: an escalating relationship with dextromethorphan [abstract #97]. Journal of Medical Toxicology. 2015
- Estimating the financial impact of adopting the revised United Kingdom acetaminophen treatment nomogram in the US population [abstract #251]. Clinical Toxicology (Philadelphia, Pa.). 2015
- Estimating the impact of adopting the revised United Kingdom acetaminophen treatment nomogram in the US population [abstract]. Journal of Medical Toxicology. 2015
- Hypoglycemia in acetaminophen-induced hepatic failure: what's the significance [abstract]?. Annals of Emergency Medicine. 2015
- Intravenous fat emulsion does not significantly alter clotting markers in dabigatran-treated blood [abstract #20]. Journal of Medical Toxicology. 2015
- Pediatric bupropion overdose mimics clinical brain death [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2014
- A swine model of severe propranolol toxicity permitting direct measurement of cerebral oxygen tension [abstract]. Journal of Medical Toxicology. 2013
- Hydroxychloroquine overdose treated successfully with intravenous fat emulsion [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2013
- Surfactant administration as treatment for respiratory failure following hydrocarbon aspiration [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2013
- A rat model of carbon monoxide induced neurotoxicity [abstract]. Academic Emergency Medicine. 2012
- Comparison of vasopressors versus placebo in beta blocker toxicity in a porcine model [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2012
- Correlation of osmolar gap and ethylene glycol concentration during dialysis [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2012
- Hydroxocobalamin hinders hemodialysis [abstract]. Clinical Toxicology (Philadelphia, Pa.). 2012
- The role of early notification from a social networking site in intentional cyanide ingestion [abstract #230]. Clinical Toxicology (Philadelphia, Pa.). 2012
Document
- High dose insulin dosing study in toxic cardiogenic shock 2012

presentations