Creating a coordinated complex outpatient antibiotic therapy program to improve outcomes and reduce costs in a multihospital system Journal Article uri icon
Overview
abstract
  • Patients leaving the hospital with severe infections requiring prolonged antibiotic
    treatment face significant risks without vigilant monitoring, especially where access
    to infectious disease specialists is limited. At HealthPartners, care after discharge was
    historically disjointed and often left to primary care providers to coordinate. In 2023,
    the health system’s Antimicrobial Stewardship Program found 13 errors over 6 weeks
    across 5 hospitals, largely due to fragmented oversight and limited access to specialists.
    In response, the health system established a centralized complex outpatient antibiotic
    therapy program in 2024 to support discharged patients.
    A survey of hospital staff found that 96% reported increased
    confidence in patient care after the program was implemented. The cost of the
    necessary investments in structured oversight may be offset through reductions in
    hospital length of stay.

  • Link to Article
    publication date
  • 2026
  • published in
  • NEJM Catalyst  Journal
  • Research
    keywords
  • Antibiotics
  • Drugs and Drug Therapy
  • Economics
  • Infectious Diseases
  • Additional Document Info
    volume
  • 7
  • issue
  • 7