Our research in oncology encompasses the full spectrum of cancer care including cancer prevention, screening and early detection, diagnosis, treatment, and survivorship, as part of the Metro-Minnesota Community Oncology Research Consortium (MMCORC). Areas of focus for our group include electronic monitoring of symptoms and use of cannabis in oncology patients. Aims of the center are to promote access to clinical trials, to share the results this research, and to advance the science of cancer treatment and care delivery. 

  • Hurley, Peter J., MD   Sr, Investigator  
  • Affiliation
    Faculty Position
  • Anderson, Daniel M., MD, MPH, Principal Investigator, Metro-Minnesota Community Oncology Research Consortium 2003 -
  • Blazar, Michael B., MD, Research Investigator & Oncologist 2019 -
  • Chen, Cathleen, MD, Hematologist/Oncologist
  • Demel, Kurt C., MD, MBA, Investigator, Metro-Minnesota Community Oncology Research Consortium
  • Ganesan, Chitra, MBBS, Hematologist/Oncologist
  • Hurley, Peter J., MD, Research Investigator
  • Hurley, Randy W., MD, Investigator, Metro-Minnesota Community Oncology Research Consortium 1995 -
  • Jaffe, Jeffrry P., MD, Investigator, Metro-Minnesota Community Oncology Research Consortium
  • Jahagirdar, Balkrishna N., MBBS, Investigator, Metro-Minnesota Community Oncology Research Consortium
  • Ji, Yan, MD, PhD, MS, Hematologist/Oncologist
  • Kubiak, Kendra, MD, Hematologist/Oncologist
  • Larson, Brenda, MD, Oncologist
  • Lerner, Rachel E., MD, MS, Co-director of oncology research, HealthPartners Institute, and investigator, Metro-Minnesota Community Oncology Research Consortium
  • McCormack, Steve E. MD, Investigator, Metro-Minnesota Community Oncology Research Consortium
  • Menge, Mark R., MD, Oncologist
  • Moore, Kathryn, MD, Hematologist/Oncologist
  • Rabenau, Karen E., MD, Hematologist/Oncologist
  • Shapiro, Alice C., PhD, RDN, Senior Research Scientist
  • Sherman, Melissa M., MD, Hematologist/Oncologist
  • Spomer, Amy, MD, Oncologist
  • Wadhwa, Punit, MD, Hematologist/Oncologist
  • Wilkowske, Mark, MD, Oncologist
  • Zylla, Dylan M., MD, MS, Investigator, Metro-Minnesota Community Oncology Research Consortium 2012 -
  • Publications While At HealthPartners
    selected publications
    Journal Article
  • PRESTO: a phase III, open-label study of intensification of androgen blockade in patients with high-risk biochemically relapsed castration-sensitive prostate cancer (AFT-19)
    Journal of Clinical Oncology. 2024
  • Development and validation of an integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit
    Commun Med (Lond). 2023
  • Life-threatening "hyper-progression" on immunotherapy revealed as pseudo-progression in DNA mismatch repair deficiency: a case report
    Journal of Gastrointestinal Oncology. 2023
  • Validation of immunotherapy response score as predictive of pan-solid tumor anti-PD-1/PD-L1 benefit
    Cancer Res Commun. 2023
  • Effect of electronic symptom monitoring on patient-reported outcomes among patients with metastatic cancer: a randomized clinical trial
    JAMA. 2022
  • Holy smokes! Developing a cannabis clinic for patients with cancer
    Oncol Issues. 2022
  • Organizational characteristics and smoking cessation support in community-based lung cancer screening programs
    Journal of the American College of Radiology. 2022
  • Orteronel for metastatic hormone-sensitive prostate cancer: a multicenter, randomized, open-label phase III trial (SWOG-1216)
    Journal of Clinical Oncology. 2022
  • A randomized trial of medical cannabis in patients with stage IV cancers to assess feasibility, dose requirements, impact on pain and opioid use, safety, and overall patient satisfaction
    Supportive Care in Cancer. 2021
  • Association of adiponectin and vitamin D with tumor infiltrating lymphocytes and survival in stage III colon cancer
    JNCI cancer spectrum. 2021
  • Monitoring rates of malnutrition risk in outpatient cancer centers utilizing the malnutrition screening tool embedded into the electronic health record
    Journal of the Academy of Nutrition and Dietetics. 2021
  • Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study
    Lancet Oncology. 2021
  • Population-adjusted indirect treatment comparison of the SOLO1 and PAOLA-1/ENGOT-ov25 trials evaluating maintenance olaparib or bevacizumab or the combination of both in newly diagnosed, advanced BRCA-mutated ovarian cancer
    European Journal of Cancer. 2021
  • Real-world performance of a comprehensive genomic profiling test optimized for small tumor samples
    JCO precision oncology. 2021
  • A randomized phase 2 study of temsirolimus and cetuximab versus temsirolimus alone in recurrent/metastatic, cetuximab-resistant head and neck cancer: the MAESTRO study
    Cancer. 2020
  • Apixaban and dalteparin in active malignancy-associated venous thromboembolism: the ADAM VTE trial
    Journal of Thrombosis and Haemostasis. 2020
  • Collection of electronic patient-reported symptoms in patients with advanced cancer using Epic MyChart surveys
    Supportive Care in Cancer. 2020
  • Immunoglobulin restores immune responses to BTH1677 in patients with low levels of antibodies to beta-glucan
    Anticancer Research. 2020
  • Impact of pain, opioids, and the mu-opioid receptor on progression and survival in patients with newly diagnosed stage IV pancreatic cancer
    American Journal of Clinical Oncology. 2020
  • Multisite, randomized trial of early integrated palliative and oncology care in patients with advanced lung and gastrointestinal cancer: Alliance A221303
    Journal of Palliative Medicine. 2020
  • Performance measures based on how adults with cancer feel and function: stakeholder recommendations and feasibility testing in six cancer centers
    JCO Oncol Pract. 2020
  • Phase 1 study of TTC-352 in patients with metastatic breast cancer progressing on endocrine and CDK4/6 inhibitor therapy
    Breast Cancer Research and Treatment. 2020
  • Randomized trial of lenalidomide versus observation in smoldering multiple myeloma
    Journal of Clinical Oncology. 2020
  • Sequencing ipilimumab immunotherapy before or after chemotherapy (nab-paclitaxel and bevacizumab) for the treatment of BRAFwt (BRAF wild-type) metastatic malignant melanoma: results of a study of Academic and Community Cancer Research United (ACCRU) RU261206I
    American Journal of Clinical Oncology. 2020
  • Two malignancies with differential responses to immune checkpoint inhibitors: a case report
    Anticancer Research. 2020
  • A phase 1 and randomized, placebo-controlled phase 2 trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma: Alliance/North Central Cancer Treatment Group N0872
    Cancer. 2019
  • Impact of diabetes and hyperglycemia on health care utilization, infection risk, and survival in patients with cancer receiving glucocorticoids with chemotherapy
    Journal of Diabetes and Its Complications. 2019
  • Impact of medical cannabis on patient-reported symptoms for patients with cancer enrolled in Minnesota's Medical Cannabis Program
    Journal of Oncology Practice. 2019
  • Randomized controlled trial of individualized treatment summary and survivorship care plans for hematopoietic cell transplantation survivors
    Haematologica. 2019
  • Tailoring a survivorship care plan: patient and provider preferences for recipients of hematopoietic cell transplantation
    Biology of Blood and Marrow Transplantation. 2019
  • Atezolizumab for first-line treatment of metastatic nonsquamous NSCLC
    New England Journal of Medicine. 2018
  • Eating, activity, and weight-related problems from adolescence to adulthood
    American Journal of Preventive Medicine. 2018
  • Impact of opioid use on health care utilization and survival in patients with newly diagnosed stage IV malignancies
    Supportive Care in Cancer. 2018
  • Nab-paclitaxel and gemcitabine as first-line treatment of advanced or metastatic cholangiocarcinoma: a phase 2 clinical trial
    JAMA oncology. 2018
  • Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, phase 2 trials
    Lancet Oncology. 2018
  • Oncology clinicians and the Minnesota Medical Cannabis Program: a survey on medical cannabis practice patterns, barriers to enrollment, and educational needs
    Cannabis and cannabinoid research. 2018
  • Physical activity and outcomes in patients with stage III colon cancer: a correlative analysis of Phase III Trial NCCTG N0147 (Alliance)
    Cancer Epidemiology, Biomarkers and Prevention. 2018
  • Response to Osimertinib in an EGFR Exon 20 insertion-positive lung adenocarcinoma
    Journal of Thoracic Oncology. 2018
  • Single-agent ibrutinib in relapsed or refractory follicular lymphoma: a phase 2 consortium trial
    Blood. 2018
  • Anaplastic mast cell sarcoma: a unique pathologic entity in mastocytosis
    Leukemia and Lymphoma. 2017
  • Establishment of personalized pain goals in oncology patients to improve care and decrease costs
    Journal of Oncology Practice. 2017
  • Family history of colorectal cancer and its impact on survival in patients with resected stage III colon cancer: results from NCCTG Trial N0147 (Alliance)
    Journal of Gastrointestinal Oncology. 2017
  • Implementation of routine postpartum depression screening and care initiation across a multispecialty health care organization: an 18-month retrospective analysis
    Maternal and child health journal. 2017
  • Intentional weight loss and endometrial cancer risk
    Journal of Clinical Oncology. 2017
  • Providing breast cancer survivorship: lessons learned from a pilot project implementation
    Cancer Nursing. 2017
  • Teaching quality improvement in Tanzania: a model of inter-professional partnership for global health development
  • The financial toll of cancer therapy: developing ways to help the patient
    Minn Physician. 2017
  • Cardiovascular complications of hematopoietic stem cell transplantation
    Current Treatment Options in Cardiovascular Medicine. 2016
  • Erlotinib, cabozantinib, or erlotinib plus cabozantinib as second-line or third-line treatment of patients with EGFR wild-type advanced non-small-cell lung cancer (ECOG-ACRIN 1512): a randomised, controlled, open-label, multicentre, phase 2 trial
    Lancet Oncology. 2016
  • Phase I study of pazopanib and ixabepilone in patients with solid tumors
    American Journal of Clinical Oncology. 2016
  • Quantification of pain in sickle mice using facial expressions and body measurements
    Blood Cells, Molecules, and Diseases. 2016
  • Ramucirumab combined with FOLFOX as front-line therapy for advanced esophageal, gastroesophageal junction, or gastric adenocarcinoma: a randomized, double-blind, multicenter Phase II trial
    Annals of Oncology. 2016
  • Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS)
    Breast Cancer Research and Treatment. 2016
  • Wound care: multicenter feasibility study
  • A randomized comparison of once weekly epoetin alfa to extended schedule epoetin or darbepoetin in chemotherapy-associated anemia
    American Journal of Hematology. 2015
  • Hematopoietic stem cell transplantation in patients with systolic dysfunction: can it be done?
    Biology of Blood and Marrow Transplantation. 2015
  • North Central Cancer Treatment Group N10C2 (Alliance): a double-blind placebo-controlled study of magnesium supplements to reduce menopausal hot flashes
    Menopause (New York, N.Y.). 2015
  • Pre-existing diabetes and breast cancer prognosis among elderly women
    British Journal of Cancer. 2015
  • Utility of high-sensitivity cardiac troponin T in patients receiving anthracycline chemotherapy
  • Association between diabetes, diabetes treatment and risk of developing endometrial cancer
    British Journal of Cancer. 2014
  • Association of opioid requirement and cancer pain with survival in advanced non-small cell lung cancer
    British Journal of Anaesthesia. 2014
  • Cancer rehabilitation: outcome evaluation of a strengthening and conditioning program
    Cancer Nursing. 2014
  • Diabetes, diabetes treatment and breast cancer prognosis
    Breast Cancer Research and Treatment. 2014
  • NCCTG N0821 (Alliance): a phase II first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cancer with good performance status
    Journal of Thoracic Oncology. 2014
  • Identification of tools to measure changes in musculoskeletal symptoms and physical functioning in women with breast cancer receiving aromatase inhibitors
    Oncology Nursing Forum. 2013
  • Opioid requirement, opioid receptor expression, and clinical outcomes in patients with advanced prostate cancer
    Cancer. 2013
  • Smoking and diabetes: does the increased risk ever go away?
    American Journal of Epidemiology. 2013
  • Changes in weight and body composition in women receiving chemotherapy for breast cancer
    Clinical Breast Cancer. 2011
  • Nutritional challenges during treatment for lung cancer
    Oncology Nursing Forum. 2011
  • N0332 phase 2 trial of weekly irinotecan hydrochloride and docetaxel in refractory metastatic breast cancer: a North Central Cancer Treatment Group (NCCTG) Trial
    Annals of Oncology. 2010
  • Effects of exercise vs bisphosphonates on bone mineral density in breast cancer patients receiving chemotherapy
    Journal of Supportive Oncology. 2009
  • Implementing a low-fat eating plan in the Women's Intervention Nutrition Study
    Journal of the American Dietetic Association. 2009
  • Impact of chemotherapy in women with metastatic breast cancer diagnosed 1990-2003
    Clinical Breast Cancer. 2007
  • Interventions to prevent loss of bone mineral density in women receiving chemotherapy for breast cancer
    Clinical Journal of Oncology Nursing. 2005
  • Evaluation of the hypercoagulable state. Whom to screen, how to test and treat
    Postgraduate Medicine. 2000
  • The hematopoietic microenvironment: stromal extracellular matrix components as growth regulators for human hematopoietic progenitors
    Hematology (Amsterdam, Netherlands). 1999
  • Quick Info