Crain, Lauren, PhD
Sr. Research Investigator and Statistician

Positions

Sr. Research Investigator and Statistician, Research Methodologies Group
Sr. Research Investigator & Statistician, Center for Chronic Care Innovation 2001 -

Joined the Institute: 2001

Education and training: PhD, social psychology, University of Kansas; MS, social psychology, University of California, Santa Cruz.

Overview/research interests: Psychological and social factors related to the initiation and maintenance of preventive health behavior; analysis of correlated data structures, including group-randomized interventions, repeated measures designs, and hierarchically structured observational data; and structural equation modeling.

Current research activities and funding:

Co-investigator on several federally funded projects focusing on preventive health behaviors, including randomized trials targeting physical activity and weight maintenance (Net-WORKS, Healthy Homes/Healthy Kids, Keep It Off, Keep Active Minnesota) and an observational study of working mothers to assess intra-individual relationships between work-family balance and preventive health behaviors
Co-investigator on two hierarchically structured cross-sectional surveys of academic researchers investigating relationships between perceptions of the research climate, organizational justice, and responsible conduct of research (Procedural Justice, Identity and Research Integrity; Propagating the Uniform Research Integrity Climate Assessment)
Co-investigator, DIAMOND Study: Evaluation of a Natural Experiment to Improve Statewide Depression Care in Minnesota, which uses staggered implementation to evaluate system-level changes in the treatment of depression in primary care clinics across Minnesota

Publications

Publications

selected publications

Journal Article
- Design of a pragmatic cluster-randomized trial comparing telehealth care and best practice clinic-based care for uncontrolled high blood pressure. Contemporary Clinical Trials. 2020
- Pragmatic trial design of an intervention to reduce cardiovascular risk in people with serious mental illness. Contemporary Clinical Trials. 2020
- The Healthy Homes/Healthy Kids 5-10 Obesity Prevention Trial: 12 and 24-month outcomes. Pediatric Obesity. 2019
- Clinical decision support directed to primary care patients and providers reduces cardiovascular risk: a randomized trial. Journal of the American Medical Informatics Association. 2018
- Mediators of weight loss maintenance in the Keep It Off Trial. Annals of Behavioral Medicine. 2018
- Multicomponent obesity prevention intervention in low-income preschoolers: primary and subgroup analyses of the NET-Works Randomized Clinical Trial, 2012-2017. American Journal of Public Health. 2018
- Clinician burnout and satisfaction with resources in caring for complex patients. General Hospital Psychiatry. 2017
- Impact of a national collaborative care initiative for patients with depression and diabetes or cardiovascular disease. General Hospital Psychiatry. 2017
- The challenges of collecting and using patient care data from diverse care systems: lessons From COMPASS. American Journal of Medical Quality. 2017
- A statewide effort to implement collaborative care for depression: reach and impact for all patients with depression. Medical Care. 2016
- Predictors of poor response to depression treatment in primary care. Psychiatric Services. 2016
- The BestFIT trial: A SMART approach to developing individualized weight loss treatments. Contemporary Clinical Trials. 2016
- The effects of patient-centered depression care on patient satisfaction and depression remission. Family Practice. 2016
- A stepped-wedge evaluation of an initiative to spread the collaborative care model for depression in primary care. Annals of Family Medicine. 2015
- Activity patterns of preschool-aged children at risk for obesity. Journal of physical activity & health. 2015
- Household factors, family behavior patterns, and adherence to dietary and physical activity guidelines among children at risk for obesity. Journal of Nutrition Education and Behavior. 2015
- Organizational factors and change strategies associated with medical home transformation. American Journal of Medical Quality. 2015
- Pediatric primary care-based obesity prevention for parents of preschool children: a pilot study 2015
- Assessing organizational readiness for depression care quality improvement: relative commitment and implementation capability. Implementation science. 2014
- Binge eating behavior and weight loss maintenance over a 2-year period. Journal of Obesity. 2014
- Challenges of medical home transformation reported by 118 patient-centered medical home (PCMH) leaders. Journal of the American Board of Family Medicine. 2014
- Concern about child weight among parents of children at-risk for obesity 2014
- How much shared decision making occurs in usual primary care of depression? . Journal of the American Board of Family Medicine. 2014
- Job design and ethnic differences in working women's physical activity. American Journal of Health Behavior. 2014
- Patient experience and physician/staff satisfaction in transforming medical homes 2014
- Predicting child physical activity and screen time: parental support for physical activity and general parenting styles. Journal of Pediatric Psychology. 2014
- Self-reported activity and accelerometry in 2 behavior-maintenance trials. American Journal of Health Behavior. 2014
- The effect of depression treatment on work productivity. American Journal of Managed Care. 2014
- Validity of diabetes self-reports in the Women's Health Initiative. Menopause (New York, N.Y.). 2014
- Designing and implementing research on a statewide quality improvement initiative: the DIAMOND study and initiative. Medical Care. 2013
- Development and validation of the Survey of Organizational Research Climate (SORC) 2013
- Enhancing long-term weight loss maintenance: 2 year results from the Keep It Off randomized controlled trial. Preventive Medicine. 2013
- Healthy Homes/Healthy Kids: a randomized trial of a pediatric primary care-based obesity prevention intervention for at-risk 5-10 year olds. Contemporary Clinical Trials. 2013
- Medical home transformation: a gradual process and a continuum of attainment. Annals of Family Medicine. 2013
- Mindfulness-based stress reduction for family caregivers: a randomized controlled trial. The Gerontologist. 2013
- NET-Works: Linking families, communities and primary care to prevent obesity in preschool-age children. Contemporary Clinical Trials. 2013
- Relationships between the Survey of Organizational Research Climate (SORC) and self-reported research practices 2013
- Self-report compared to electronic medical record across eight adult vaccines: do results vary by demographic factors?. Vaccine. 2013
- The DIAMOND initiative: implementing collaborative care for depression in 75 primary care clinics. Implementation science. 2013
- Keep it off: a phone-based intervention for long-term weight-loss maintenance. Contemporary Clinical Trials. 2011
- Prevalence of practice system tools for improving depression care among primary care clinics: the DIAMOND initiative. Journal of General Internal Medicine. 2011
- Recruiting and retaining family caregivers to a randomized controlled trial on mindfulness-based stress reduction. Contemporary Clinical Trials. 2011
- Severity of depression and magnitude of productivity loss. Annals of Family Medicine. 2011
- The Use of Telehealth Technology in Assessing the Accuracy of Self-Reported Weight and the Impact of a Daily Immediate-Feedback Intervention among Obese Employees 2011
- Maintaining physical activity among older adults: 24-month outcomes of the Keep Active Minnesota randomized controlled trial. Preventive Medicine. 2010
- Partnership research: a practical trial design for evaluation of a natural experiment to improve depression care. Medical Care. 2010
- Population reach and recruitment bias in a maintenance RCT in physically active older adults. Journal of physical activity & health. 2010
- The importance of organizational justice in ensuring research integrity 2010
- The long and winding road to physical activity maintenance. American Journal of Health Behavior. 2010
- Customized feedback to patients and providers failed to improve safety or quality of diabetes care: a randomized trial. Diabetes care. 2009
- Diabetes care quality: insurance, health plan, and physician group contributions. American Journal of Managed Care. 2009
- Does diabetes double the risk of depression?. Annals of Family Medicine. 2009
- Effects of paroxetine and sertraline on low-density lipoprotein cholesterol: an observational cohort study 2009
- Institutions' expectations for researchers' self-funding, federal grant holding, and private industry involvement: manifold drivers of self-interest and researcher behavior. Academic Medicine. 2009
- Self-weighing promotes weight loss for obese adults. American Journal of Preventive Medicine. 2009
- Telephone counseling and home telemonitoring: the Weigh by Day Trial. American Journal of Health Behavior. 2009
- A new approach to physical activity maintenance: rationale, design, and baseline data from the Keep Active Minnesota Trial. BMC Geriatrics. 2008
- Maintaining physical activity among older adults: six-month outcomes of the Keep Active Minnesota randomized controlled trial. Preventive Medicine. 2008
- The effect of advanced access implementation on quality of diabetes care. Preventing Chronic Disease. 2008
- Tobacco-use prevalence in special populations taking advantage of electronic medical records. American Journal of Preventive Medicine. 2008
- Variation in quality of diabetes care at the levels of patient, physician, and clinic. Preventing Chronic Disease. 2008
- Ambulatory care quality measures for the 6 aims from administrative data. American Journal of Medical Quality. 2006
- Care quality and implementation of the chronic care model: a quantitative study. Annals of Family Medicine. 2006
- Effect of improved primary care access on quality of depression care. Annals of Family Medicine. 2006
- Scientists' perceptions of organizational justice and self-reported misbehaviors 2006
- Health care charges associated with physical inactivity, overweight, and obesity. Preventing Chronic Disease. 2005
- Impact of an electronic medical record on diabetes quality of care. Annals of Family Medicine. 2005
- Insurance status and access to urgent ambulatory care follow-up appointments. JAMA. 2005
- Randomized trial of quality improvement intervention to improve diabetes care in primary care settings. Diabetes care. 2005
- Do all components of the chronic care model contribute equally to quality improvement? 2004
- Does improved access to care affect utilization and costs for patients with chronic conditions?. American Journal of Managed Care. 2004
- Health and performance factors in health care shift workers. Journal of Occupational and Environmental Medicine. 2004
- Is patient readiness to change a predictor of improved glycemic control?. Diabetes care. 2004
- Measuring patient safety in ambulatory care: potential for identifying medical group drug-drug interaction rates using claims data. American Journal of Managed Care. 2004
- Meeting recommendations for multiple healthy lifestyle factors. Prevalence, clustering, and predictors among adolescent, adult, and senior health plan members. American Journal of Preventive Medicine. 2004
- Changes in physical activity and short-term changes in health care charges: a prospective cohort study of older adults. Preventive Medicine. 2003
Editorial Article
- Risk and benefit information and use of aspirin [editorial]. JAMA internal medicine. 177. 2017
- Self-reported diabetes is a valid outcome in pragmatic clinical trials and observational studies [editorial]. Journal of Clinical Epidemiology. 66. 2013
Conference Poster
Abstract
- Differences in chronic kidney disease management in patients with and without diabetes in a large care delivery system [abstract]. Diabetes. 2020
- A web-based clinical decision support system (Wizard) increases appropriate cardiometabolic diagnostic coding at primary care visits [abstract]. Journal of patient-centered research and reviews. 2019
- Dissemination and sustained use of an outpatient clinical decision system with high use rates, high clinician satisfaction, and positive impact on quality of care [abstract]. Journal of patient-centered research and reviews. 2019
- Variation in care improvement opportunities suggests need for tailored clinician-specific improvement interventions [abstract]. Journal of patient-centered research and reviews. 2019
- A clinical decision support system promotes shared decision-making and cardiovascular risk factor management [abstract]. Journal of patient-centered research and reviews. 2016
- Comparative effectiveness of two diabetes clinical decision support systems on cardiometabolic outcomes and CV risk: randomized trial [abstract 2304-PUB]. Diabetes. 2016
- Design features of successful outpatient chronic disease care clinical decision support systems [abstract]. Journal of patient-centered research and reviews. 2016
- Eliciting patient treatment preferences using a clinical decision support system [abstract 1252-P]. Diabetes. 2016
- Overuse and underuse of acetyl-salicylic acid for primary prevention of cardiovascular disease in people with diabetes [abstract]. Diabetologia. 2016
- Overuse and underuse of aspirin for primary prevention [abstract 1225-P]. Diabetes. 2016
- Overuse and underuse of aspirin for primary prevention of cardiovascular events in primary care [abstract]. Journal of patient-centered research and reviews. 2016
- Randomised trial of a diabetes clinical decision support system: use rates, provider satisfaction, and impact on clinical outcomes [abstract]. Diabetologia. 2016
- The BestFIT Weight Loss Trial: smart study design and early implementation lessons learned [abstract]. Annals of Behavioral Medicine. 2016
- Achieving clinically significant weight loss: how soon can we respond to non-responders [abstract]?. Annals of Behavioral Medicine. 2015
- Evaluation of provider experience with an EHR-based clinical decision support tool [abstract 2643-PO]. Diabetes. 2015
- Sustained use of a diabetes clinical decision support tool in primary care practices [abstract 1340-P]. Diabetes. 2015
- Testing a clinical decision support process to lower cardiovascular risk of patients [abstract]. Clinical Medicine & Research. 2013

presentations

Presentation