Qualitative research that prioritizes the voice of individuals with cognitive impairment (CI) is critical to better understand the diversity and nuances of care experiences of this population. Yet, challenges to conducting qualitative studies, specifically semi-structured interviews, exist with individuals with CI. This manuscript describes the rapid qualitative approach used to design, conduct, and analyze dyad phone interviews with individuals with CI and their care partners. We also reflect on the benefits and challenges of using a rapid approach with this population and discuss recommendations for future research. Overall, these methods were successful in gathering data to answer research questions in an efficient and pragmatic way. Future recommendations include partnering with clinical content area experts who can provide guidance on all phases of the study, as well as utilizing rapid qualitative analysis methods to make research with individuals with CI more feasible for a wider range of researchers.