About

Our research in pulmonology includes clinical trials and observational studies. Our research focuses on pulmonary conditions including chronic obstructive pulmonary disease (COPD), asthma, lung nodules, sarcoidosis, and sleep disorders. We participate in multi-site research networks including COPDGene®.
Affiliation
people
Faculty Position
  • McEvoy, Charlene E., MD, MPH, Clinical Investigator
    • Publications While At Healthpartners
    selected publications
    Journal Article
  • A randomised trial of anti-GM-CSF Otilimab in severe COVID-19 pneumonia (OSCAR). 
    European Respiratory Journal. 2023
  • Accuracy of COVID-19-like illness diagnoses in electronic health record data: retrospective cohort study. 
    JMIR formative research. 2023
  • Estimation of COVID-19 mRNA vaccine effectiveness and COVID-19 illness and severity by vaccination status during Omicron BA.4 and BA.5 sublineage periods. 
    JAMA network open. 2023
  • Bronchial thermoplasty in patients with severe asthma at 5 years: the Post-FDA Approval Clinical Trial Evaluating Bronchial Thermoplasty in Severe Persistent Asthma study. 
    Chest. 2022
  • Bronchodilators in tobacco-exposed persons with symptoms and preserved lung function. 
    New England Journal of Medicine. 2022
  • Early estimates of bivalent mRNA vaccine effectiveness in preventing COVID-19-associated emergency department or urgent care encounters and hospitalizations among immunocompetent adults - VISION Network, nine states, September-November 2022. 
    MMWR: Morbidity and Mortality Weekly Report. 2022
  • Effectiveness of 2, 3, and 4 COVID-19 mRNA vaccine doses among immunocompetent adults during periods when SARS-CoV-2 Omicron BA.1 and BA.2/BA.2.12.1 sublineages predominated - VISION Network, 10 states, December 2021-June 2022. 
    MMWR: Morbidity and Mortality Weekly Report. 2022
  • Effectiveness of COVID-19 mRNA vaccines against COVID-19-associated hospitalizations among immunocompromised adults during SARS-CoV-2 Omicron predominance - VISION Network, 10 states, December 2021-August 2022. 
    MMWR: Morbidity and Mortality Weekly Report. 2022
  • Effectiveness of a third dose of mRNA vaccines against COVID-19-associated emergency department and urgent care encounters and hospitalizations among adults during oeriods of Delta and Omicron variant predominance - VISION Network, 10 states, August 2021-January 2022. 
    MMWR: Morbidity and Mortality Weekly Report. 2022
  • Effectiveness of homologous and heterologous COVID-19 booster doses following 1 Ad.26.COV2.S (Janssen [Johnson & Johnson]) vaccine dose against COVID-19-associated emergency department and urgent care encounters and hospitalizations among adults - VISION Network, 10 states, December 2021-March 2022. 
    MMWR: Morbidity and Mortality Weekly Report. 2022
  • Effectiveness of two-dose vaccination with mRNA COVID-19 vaccines against COVID-19-associated hospitalizations among immunocompromised adults-nine states, January-September 2021. 
    American Journal of Transplantation. 2022
  • Promoting chronic obstructive pulmonary disease wellness through remote monitoring and health coaching: a clinical trial. 
    Annals of the American Thoracic Society. 2022
  • Waning 2-dose and 3-dose effectiveness of mRNA vaccines against COVID-19-associated emergency department and urgent care encounters and hospitalizations among adults during periods of Delta and Omicron variant predominance - VISION Network, 10 states, August 2021-January 2022. 
    MMWR: Morbidity and Mortality Weekly Report. 2022
  • Waning of vaccine effectiveness against moderate and severe covid-19 among adults in the US from the VISION network: test negative, case-control study. 
    BMJ (Clinical research ed.). 2022
  • Chronic bronchitis in COPD patients creates worse symptom burden regardless of the presence of bronchiectasis in the COPDGene cohort. 
    Chronic obstructive pulmonary diseases (Miami, Fla.). 2021
  • Effectiveness of 2-dose vaccination with mRNA COVID-19 vaccines against COVID-19-associated hospitalizations among immunocompromised adults - nine states, January-September 2021. 
    MMWR: Morbidity and Mortality Weekly Report. 2021
  • Laboratory-confirmed COVID-19 among adults hospitalized with COVID-19-like illness with infection-induced or mRNA vaccine-induced SARS-CoV-2 immunity - nine states, January-September 2021. 
    MMWR: Morbidity and Mortality Weekly Report. 2021
  • Phase 3 safety and efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 vaccine. 
    New England Journal of Medicine. 2021
  • Safety and effectiveness of bronchial thermoplasty after 10 years in patients with persistent asthma (BT10+): a follow-up of three randomised controlled trials. 
    The Lancet. Respiratory medicine. 2021
  • COPDGene(®) 2019: redefining the diagnosis of chronic obstructive pulmonary disease. 
    Chronic obstructive pulmonary diseases (Miami, Fla.). 2019
  • Effect of health coaching delivered by a respiratory therapist or nurse on self-management abilities in severe COPD: analysis of a large randomized study. 
    Respiratory Care. 2019
  • Metoprolol for the prevention of acute exacerbations of COPD. 
    New England Journal of Medicine. 2019
  • Effect of beta-blockers on exacerbation rate and lung function in chronic obstructive pulmonary disease (COPD). 
    Respiratory Research. 2017
  • Health coaching in severe COPD after a hospitalization: a qualitative analysis of a large randomized study. 
    Respiratory Care. 2017
  • Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies. 
    European Respiratory Journal. 2017
  • Severe polyserositis induced by the 13-valent pneumococcal conjugate vaccine: a case report
    2017
  • Health coaching and chronic obstructive pulmonary disease rehospitalization. a randomized study. 
    American Journal of Respiratory and Critical Care Medicine. 2016
  • High-dose oral N-acetylcysteine fails to improve respiratory health status in patients with chronic obstructive pulmonary disease and chronic bronchitis: a randomized, placebo-controlled trial. 
    International Journal of Chronic Obstructive Pulmonary Disease. 2016
  • Clinical and radiologic disease in smokers with normal spirometry. 
    JAMA internal medicine. 2015
  • Implementation of physical activity programs after COPD hospitalizations: lessons from a randomized study. 
    Chronic Respiratory Disease. 2015
  • Self-reported sleep quality and acute exacerbations of chronic obstructive pulmonary disease. 
    International Journal of Chronic Obstructive Pulmonary Disease. 2015
  • Healthcare utilization and costs in persons with insomnia in a managed care population. 
    American Journal of Managed Care. 2014
  • Bronchial thermoplasty: long-term safety and effectiveness in patients with severe persistent asthma. 
    Journal of Allergy and Clinical Immunology. 2013
  • Development and feasibility of a self-management intervention for chronic obstructive pulmonary disease delivered with motivational interviewing strategies. 
    Journal of Cardiopulmonary Rehabilitation and Prevention. 2013
  • Influence of lightweight ambulatory oxygen on oxygen use and activity patterns of COPD patients receiving long-term oxygen therapy. 
    COPD. 2012
  • Long-term comparative immunogenicity of protein conjugate and free polysaccharide pneumococcal vaccines in chronic obstructive pulmonary disease. 
    Clinical Infectious Diseases. 2012
  • Azithromycin for prevention of exacerbations of COPD. 
    New England Journal of Medicine. 2011
  • Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study. 
    American Journal of Respiratory and Critical Care Medicine. 2011
  • Epidemiology, radiology, and genetics of nicotine dependence in COPD. 
    Respiratory Research. 2011
  • Lung volumes and emphysema in smokers with interstitial lung abnormalities. 
    New England Journal of Medicine. 2011
  • Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization. 
    COPD. 2011
  • Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. 
    American Journal of Respiratory and Critical Care Medicine. 2010
  • AIR2Trial: bronchial thermoplasty for asthma: changing the landscape for future treatment. 
    Advance for Managers of Respiratory Care. 2007
  • Association between corticosteroid use and vertebral fractures in older men with chronic obstructive pulmonary disease. 
    American Journal of Respiratory and Critical Care Medicine. 1998
    • Conference Poster
  • Effects of music on exercise experience of cardiac and pulmonary rehabilitation participants [poster]
    2013
  • Health care costs and utilization in patients with insomnia: higher medical expenses and declining health often follow treatment [poster]
    2013
    • Report
  • Diagnosis and management of chronic obstructive pulmonary disease (COPD) [health care guideline]
    2011
    • Review
  • Equitable well-being, social trust, and the economy: an integrated health system's perspectives on the long-term implications of COVID-19 [review]. 
    Progress in Cardiovascular Diseases. 2022
  • Corticosteroids in chronic obstructive pulmonary disease. Clinical benefits and risks [review]. 
    Clinics in Chest Medicine. 2000
  • Adverse effects of corticosteroid therapy for COPD. A critical review [review]. 
    Chest. 1997
    • Abstract
  • Post-approval study for bronchial thermoplasty (BT): results to 2 years [abstract]. 
    American Journal of Respiratory and Critical Care Medicine. 2017
  • Sleep quality in patients with moderate to severe COPD [abstract]. 
    American Journal of Respiratory and Critical Care Medicine. 2014
  • Pilot study of sleep disturbance and lung disease in older adults [abstract]. 
    American Journal of Respiratory and Critical Care Medicine. 2010
    • Audio Document
  • The air we breathe: risks of poor indoor air quality [podcast]
    2022
    • Quick Info