Helping pulmonology patients breathe easier
Pulmonary research at HealthPartners focuses on improving the health and care of patients with lung conditions. Those conditions include chronic obstructive pulmonary disease (COPD), asthma, lung nodules and sleep disorders. We are actively involved in federally funded and industry-sponsored clinical research trials, collaborating with pulmonary experts across the country. Participation in these studies is open to HealthPartners members and community members.
To find a detailed information about our research studies that are currently enrolling participants or contact a study coordinator, click here.
COPD CRN trials
We have participated in several clinical trials to explore treatment of COPD and reduction of COPD flare-ups (shortness of breath, producing more mucous):
- AMBOX (Ambulatory Oxygen) – Use of light weight oxygen to enable increased activity levels.
- MACRO (Macrolides for COPD) – Use of daily azithromycin (antibiotic) to reduce COPD flare-ups.
- STATCOPE (SimvaSTAT in the Prevention of COPD Exacerbations) – Use of simvastatin (cholesterol-lowering drug) for reducing COPD flare-ups.
- LEUKO (Leukotrienes for COPD) – Use of zileuton (asthma drug) to treat COPD flare-ups
- BLOCK_COPD (Beta-Blockers for the Prevention of Acute Exacerbations of COPD) – We are testing how well metoprolol succinate (beta blocker) taken once per day works to reduce COPD flare-ups for patients who have moderately severe COPD. We are also testing the effect of the drug on rates and severity of COPD flare-ups, cardiovascular events, death from all causes, lung function, exercise tolerance and quality of life. This is funded by the Department of Defense
- CARE (COPD Awareness, Rehabilitation, and Empowerment) – We aimed to decrease hospital re-admissions and increase and maintain physical activity through consistent patient motivation. We used pulmonary rehabilitation and home exercise, along with goal setting and early treatment of flare ups. This was done through motivational interviewing.
- Home Pulmonary Rehab – This study is evaluating the effect of a home-based rehabilitation system on quality of life and steps. The system allows monitoring by a health care system. A health coach reviews the data and provide coaching to facilitate behavioral change and self-efficacy.
- Genetic Epidemiology of COPD – The purpose of this study is to find genetic factors that could predict who will develop COPD. It is funded by National Institutes of Health.
- INSIGHT (Intervention Study in Overweight Patients with COPD) – In this study, investigators are trying to find out if a program proven to help people lose a modest amount of weight and increase their physical activity will improve COPD symptoms for those with a high BMI. Those who want to will be able to work with a health coach to help meet weight and activity goals.
- RETHINC (REdefining THerapy IN Early COPD) – This study is evaluating a drug (indacterol/glycopyrrolate) that may help improve breathing in people who do not meet the current criteria for COPD but have respiratory symptoms such as coughing and shortness of breath.