Effectiveness of COVID-19 vaccines against Delta variant
We co-authored two studies on the effectiveness of COVID-19 vaccines against the Delta variant. Researchers looked at 30,000 urgent care visits, emergency department visits, and hospital admissions during June and July 2021, after the Delta variant was widely circulating in the United States. They determined that the effectiveness of the vaccines against COVID-19 hospitalizations and emergency and urgent care encounters remained similar to the vaccine effectiveness prior to the Delta variant predominance.
Phase 3 clinical trial for a COVID-19 vaccine
In September 2020, we began participation in the AstraZeneca COVID-19 vaccine trial. We were the first site in Minnesota to participate in a COVID-19 vaccine trial, chosen because of our strengths as an integrated system with nationally recognized clinical research expertise. Among the roughly 100 research institutions participating in the trial, our organization was one of the highest enrolling sites. Our trial participants reflected the diverse community we serve, with more than 36 percent of participants from communities of color. This diverse representation leads to better science and, ultimately, better health. Data published in the New England Journal of Medicine (NEJM) show the AstraZeneca COVID-19 vaccine is highly effective at protecting against the virus. The AstraZeneca COVID-19 vaccine is effective, affordable, relatively easy to store and critical to helping prevent COVID-19 around the world.
Safety of influenza and pertussis vaccines when given during pregnancy
The influenza and pertussis vaccines are recommended for all women during pregnancy. As part of the VSD, we led a series of studies to assess the safety of this practice. We examined mother and infant outcomes after vaccination in pregnancy. Overall, our research supports the safety of current vaccine recommendations to give pregnant women influenza and pertussis vaccines.
Safety of inadvertent exposures to HPV vaccine during pregnancy
The human papillomavirus (HPV) vaccine is not recommended in pregnancy. However, it is necessary for women of child bearing age and for those who are accidentally exposed to HPV during or around the time of pregnancy. As part of the VSD, we are currently studying whether accidental HPV exposures in pregnancy are associated with increased risk of fetal death.
Safety of live attenuated influenza vaccine in children with asthma
Children with asthma are at high risk for complications from influenza. In this study, we demonstrated the safety of a policy to administer live attenuated influenza vaccine in children with asthma. This study was funded by the National Institute of Allergy and Infectious Disease, as part of the NIH.
Learn more about our Vaccine investigators and their publications by visiting Knowledge Exchange.