member of
- Maternal and child health Senior Investigator 2010 -
Kharbanda, Elyse O., MD, MPH
Executive Director, Research
Positions
- Sr. Investigator, Center for Chronic Care Innovation 2010 -
- Sr. Research Investigator, Vaccines 2010 -
- Senior Investigator, Maternal and child health 2010 -
- Senior Research Investigator, MD, Primary care, pediatrics 2010 -
- Executive Director, Research, HealthPartners Institute 2021 -
Joined the Institute: 2010
Education and training: MD, Albert Einstein College of Medicine; MPH, Mailman School of Public Health, Columbia University.
Overview/research interests: Vaccine and drug safety and pregnancy, clinical decision support, teen pregnancy, and interventions to promote vaccine uptake.
Current research activities and funding:
• Vaccine Safety Datalink
• EHR-Based Clinical Decision Support to Improve BP Management in Adolescents (Peds and TeenBP)
• EHR-Based Decision Support for Pediatric Acute Abdominal Pain in Emergency Care (Appy CDS)
• Adolescent risk behavior screening (eTeenQ)
- Affiliation
- Publications
- View All
Affiliation
Publications
selected publications
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Journal Article
- Antibiotics prior to age 2 years have limited association with preschool growth trajectory. International Journal of Obesity (2005). 2022
- Association of the COVID-19 pandemic with routine childhood vaccination rates and proportion up to date with vaccinations across 8 US health systems in the Vaccine Safety Datalink. JAMA pediatrics. 2022
- Gestational diabetes mellitus is associated with altered abundance of exosomal microRNAs in human milk. Clinical Therapeutics. 2022
- Gestational diabetes mellitus is associated with differences in human milk hormone and cytokine concentrations in a fully breastfeeding United States cohort. Nutrients. 2022
- How to make up for rotavirus vaccination missed during the COVID-19 pandemic?-Reply. JAMA pediatrics. 2022
- Monitoring vaccine safety using the vaccine safety Datalink: assessing capacity to integrate data from Immunization Information systems. Vaccine. 2022
- Receipt of COVID-19 vaccine during pregnancy and preterm or small-for-gestational-age at birth - eight integrated health care organizations, United States, December 15, 2020-July 22, 2021. MMWR: Morbidity and Mortality Weekly Report. 2022
- "I know my body better than you:" patient focus groups to inform a decision aid on oral corticosteroid use during pregnancy. Pharmacoepidemiology and Drug Safety. 2021
- Association of inadvertent 9-valent human papillomavirus vaccine in pregnancy with spontaneous abortion and adverse birth outcomes. JAMA network open. 2021
- COVID-19 vaccination coverage among insured persons aged ≥16 years, by race/ethnicity and other selected characteristics - eight integrated health care organizations, United States, December 14, 2020-May 15, 2021. MMWR: Morbidity and Mortality Weekly Report. 2021
- Developing algorithms for identifying major structural birth defects using automated electronic health data. Pharmacoepidemiology and Drug Safety. 2021
- Effect of clinical decision support on diagnostic imaging for pediatric appendicitis: a cluster randomized trial. JAMA network open. 2021
- Effectiveness of Covid-19 vaccines in ambulatory and inpatient care settings. New England Journal of Medicine. 2021
- Human milk glucose, leptin, and insulin predict cessation of full breastfeeding and initiation of formula use. Breastfeeding Medicine. 2021
- Incidence of pediatric inflammatory bowel disease within the Vaccine Safety Datalink network and evaluation of association with rotavirus vaccination. Vaccine. 2021
- Infant sex differences in human milk intake and composition from 1- to 3-month post-delivery in a healthy United States cohort. Annals of Human Biology. 2021
- Maternal dietary intake of total fat, saturated fat, and added sugar is associated with infant adiposity and weight status at 6 mo of age. Journal of Nutrition. 2021
- Point: Uncertainty about estimating the risks of COVID-19 during pregnancy. Paediatric and Perinatal Epidemiology. 2021
- Spontaneous abortion following COVID-19 vaccination during pregnancy. JAMA. 2021
- Surveillance for adverse events after COVID-19 mRNA vaccination. JAMA. 2021
- Temporal trends in undervaccination: a population-based cohort study. American Journal of Preventive Medicine. 2021
- The childhood vaccination schedule and the lack of association with type 1 diabetes. Pediatrics. 2021
- Vaccine Safety Datalink infrastructure enhancements for evaluating the safety of maternal vaccination. Therapeutic advances in drug safety. 2021
- Association between rotavirus vaccination and type 1 diabetes in children. JAMA pediatrics. 2020
- Birth and early developmental screening outcomes associated with cannabis exposure during pregnancy. Journal of Perinatology. 2020
- Clinical decision support for recognizing and managing hypertensive blood pressure in youth: no significant impact on medical costs. Academic Pediatrics. 2020
- Diagnostic performance of emergency physician gestalt for predicting acute appendicitis in patients age 5 to 20 years. Academic Emergency Medicine. 2020
- Effects of the COVID-19 pandemic on routine pediatric vaccine ordering and administration - United States, 2020. MMWR: Morbidity and Mortality Weekly Report. 2020
- Evaluating the association of stillbirths after maternal vaccination in the Vaccine Safety Datalink. Obstetrics and Gynecology. 2020
- Improving hypertension recognition in adolescents, a small but important first step in cardiovascular disease prevention. Academic Pediatrics. 2020
- SARS-CoV-2 infection among hospitalized pregnant women: reasons for admission and pregnancy characteristics - eight U.S. health care centers, March 1-May 30, 2020. MMWR: Morbidity and Mortality Weekly Report. 2020
- Association of full breastfeeding duration with postpartum weight retention in a cohort of predominantly breastfeeding women. Nutrients. 2019
- Development of a clinical decision support system for pediatric abdominal pain in emergency department settings across two health systems within the HCSRN. EGEMS (Washington, DC). 2019
- Higher maternal diet quality during pregnancy and lactation is associated with lower infant weight-for-length, body fat percent, and fat mass in early postnatal life. Nutrients. 2019
- Impact of updated pediatric hypertension guidelines on progression from elevated blood pressure to hypertension in a community-based primary care population. Journal of Clinical Hypertension (Greenwich, Conn.). 2019
- Maternal antibiotic use during pregnancy and childhood obesity at age 5 years. International Journal of Obesity (2005). 2019
- Relationship of maternal weight status before, during, and after pregnancy with breast milk hormone concentrations. Obesity (Silver Spring, Md.). 2019
- Safety of guidelines recommending live attenuated influenza vaccine for routine use in children and adolescents with asthma. Vaccine. 2019
- Similar relative risks of seizures following measles containing vaccination in children born preterm compared to full-term without previous seizures or seizure-related disorders. Vaccine. 2019
- Text message alerts to emergency physicians identifying potential study candidates increase clinical trial enrollment. Journal of the American Medical Informatics Association. 2019
- Uptake and safety of hepatitis A vaccination during pregnancy: a Vaccine Safety Datalink study. Vaccine. 2019
- Validation of the Pediatric Appendicitis Risk Calculator (pARC) in a community emergency department setting. Annals of Emergency Medicine. 2019
- Clinical decision support for recognition and management of hypertension: a randomized trial. Pediatrics. 2018
- Development and validation of a novel Pediatric Appendicitis Risk Calculator (pARC). Pediatrics. 2018
- Evaluation of an electronic clinical decision support tool for incident elevated BP in adolescents. Academic Pediatrics. 2018
- Infant hospitalizations and mortality after maternal vaccination. Pediatrics. 2018
- Racial disparities in family-provider interactions for pediatric asthma care. Journal of Asthma. 2018
- Risk of spontaneous abortion after inadvertent human papillomavirus vaccination in pregnancy. Obstetrics and Gynecology. 2018
- Uptake and safety of Hepatitis B vaccination during pregnancy: a Vaccine Safety Datalink study. Vaccine. 2018
- Febrile seizure risk after vaccination in children one to five months of age. Pediatric Neurology. 2017
- First trimester influenza vaccination and risks for major structural birth defects in offspring. Journal of Pediatrics. 2017
- Identifying birth defects in automated data sources in the Vaccine Safety Datalink. Pharmacoepidemiology and Drug Safety. 2017
- Immunization: Vaccine Safety Datalink. Minn Physician. 2017
- Maternal Tdap vaccination and risk of infant morbidity. Vaccine. 2017
- Maternal and infant outcomes after human papillomavirus vaccination in the periconceptional period or during pregnancy. Obstetrics and Gynecology. 2017
- Spontaneous abortion and ectopic pregnancy: case definition & guidelines for data collection, analysis, and presentation of maternal immunization safety data. Vaccine. 2017
- Change in weight status and development of hypertension. Pediatrics. 2016
- Congenital anomalies: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine. 2016
- Febrile seizure risk after vaccination in children 6 to 23 months. Pediatrics. 2016
- Implementation of electronic clinical decision support for pediatric appendicitis. Pediatrics. 2016
- Influenza vaccination during pregnancy: influenza seasons 2002-2012, Vaccine Safety Datalink. American Journal of Preventive Medicine. 2016
- Maternal Tdap vaccination: coverage and acute safety outcomes in the vaccine safety datalink, 2007-2013. Vaccine. 2016
- Mismatching among guidelines, providers, and parents on controller medication use in children with asthma. The journal of allergy and clinical immunology. In practice. 2016
- Potential misclassification of blood pressure status in children and adolescents with short or tall stature. American Journal of Epidemiology. 2016
- Risk of anaphylaxis after vaccination in children and adults. Journal of Allergy and Clinical Immunology. 2016
- Risk of preterm or small-for-gestational-age birth after influenza vaccination during pregnancy: caveats when conducting retrospective observational studies. American Journal of Epidemiology. 2016
- Tdap vaccination during pregnancy and microcephaly and other structural birth defects in offspring. JAMA. 2016
- Vaccination and 30-day mortality risk in children, adolescents, and young adults. Pediatrics. 2016
- Association of Tdap vaccination with acute events and adverse birth outcomes among pregnant women with prior tetanus-containing immunizations. JAMA. 2015
- Asthma treatments and mental health visits after a Food and Drug Administration label change for leukotriene inhibitors. Clinical Therapeutics. 2015
- Comparing US paediatric and adult weight classification at the transition from late teenage to young adulthood. Pediatric Obesity. 2015
- Factors associated with adherence to blood pressure measurement recommendations at pediatric primary care visits, Minnesota and Colorado, 2007-2010. Preventing Chronic Disease. 2015
- Impacting delayed pediatric influenza vaccination: a randomized controlled trial of text message reminders. American Journal of Preventive Medicine. 2015
- Primary adherence to controller medications for asthma is poor. Annals of the American Thoracic Society. 2015
- Safety of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis and influenza vaccinations in pregnancy. Obstetrics and Gynecology. 2015
- TeenBP: development and piloting of an EHR-linked clinical decision support system to improve recognition of hypertension in adolescents. EGEMS (Washington, DC). 2015
- A comparison of confounding adjustment methods for assessment of asthma controller medication effectiveness. American Journal of Epidemiology. 2014
- Evaluation of the association of maternal pertussis vaccination with obstetric events and birth outcomes. JAMA. 2014
- Impact of hypertension on healthcare costs among children. American Journal of Managed Care. 2014
- Influenza vaccine text message reminders for urban, low-income pregnant women: a randomized controlled trial. American Journal of Public Health. 2014
- Influenza vaccine: an updated position statement of the Society for Adolescent Health and Medicine. Journal of Adolescent Health. 2014
- Initiation of oral contraceptives and changes in blood pressure and body mass index in healthy adolescents. Journal of Pediatrics. 2014
- Lipid screening in children and adolescents in community practice: 2007 to 2010. Circulation: Cardiovascular Quality and Outcomes. 2014
- Maternal influenza vaccine and risks for preterm or small for gestational age birth. Journal of Pediatrics. 2014
- Missed opportunities for pregnancy prevention among insured adolescents. JAMA pediatrics. 2014
- Monovalent H1N1 influenza vaccine safety in pregnant women, risks for acute adverse events. Vaccine. 2014
- Prevalence of obesity and extreme obesity in children aged 3-5 years. Pediatric Obesity. 2014
- Receipt of pertussis vaccine during pregnancy across 7 Vaccine Safety Datalink Sites. Preventive Medicine. 2014
- Severe obesity in children: prevalence, persistence and relation to hypertension. International Journal of Pediatric Endocrinology. 2014
- Use of leukotriene receptor antagonists are associated with a similar risk of asthma exacerbations as inhaled corticosteroids. The journal of allergy and clinical immunology. In practice. 2014
- Vaccinations given during pregnancy, 2002-2009: a descriptive study. American Journal of Preventive Medicine. 2014
- Adolescent consent for vaccination: a position paper of the Society for Adolescent Health and Medicine. Journal of Adolescent Health. 2013
- Current status and future prospects for electronic point-of-care clinical decision support in diabetes care. Current Diabetes Reports. 2013
- Identifying pregnancy episodes, outcomes, and mother-infant pairs in the Vaccine Safety Datalink. Vaccine. 2013
- Inactivated influenza vaccine during pregnancy and risks for adverse obstetric events. Obstetrics and Gynecology. 2013
- Influenza and pertussis vaccination coverage among privately insured women of reproductive age. Maternal and child health journal. 2013
- Maternal safety of trivalent inactivated influenza vaccine in pregnant women. Obstetrics and Gynecology. 2013
- Patterns of care and persistence after incident elevated blood pressure. Pediatrics. 2013
- Prehypertension and hypertension in community-based pediatric practice. Pediatrics. 2013
- Receipt of human papillomavirus vaccine among privately insured adult women in a U.S. midwestern health maintenance organization. Preventive Medicine. 2013
- Safety of the yellow fever vaccine: a retrospective study. Journal of Travel Medicine. 2013
- Statin exposure is associated with decreased asthma-related emergency department visits and oral corticosteroid use. American Journal of Respiratory and Critical Care Medicine. 2013
- Effect of a text messaging intervention on influenza vaccination in an urban, low-income pediatric and adolescent population: a randomized controlled trial. JAMA. 2012
- Identifying adolescent females at high risk of pregnancy in a pediatric emergency department. Journal of Adolescent Health. 2012
- Text4Health: impact of text message reminder-recalls for pediatric and adolescent immunizations. American Journal of Public Health. 2012
- Delivering adolescent preventive services in an office setting. Adolescent Medicine: State of the Art Reviews. 2011
- Exploring pregnant women's views on influenza vaccination and educational text messages. Preventive Medicine. 2011
- Text message reminders to promote human papillomavirus vaccination. Vaccine. 2011
- The role of human papillomavirus vaccination in promoting delivery of other preventive and medical services. Academic Pediatrics. 2011
- Changes in Tdap and MCV4 vaccine coverage following enactment of a statewide requirement of Tdap vaccination for entry into sixth grade. American Journal of Public Health. 2010
- Vaccinating teens: current guidelines, challenges, and opportunities. Pediatric Annals. 2010
- Use of influenza A (H1N1) 2009 monovalent vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009. MMWR: Recommendations and Reports. 2009
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Editorial Article
- COVID-19 mRNA vaccines during pregnancy: new evidence to help address vaccine hesitancy [editorial]. JAMA. 327. 2022
- Is Tdap the best prevention we have against pertussis disease [editorial]?. Journal of Adolescent Health. 62. 2018
- Are we measuring blood pressure correctly in children, particularly in obesity [editorial]?. Archives of Disease in Childhood. 101. 2016
- Helping mothers to get the message about influenza: are texts the future for increased immunization [editorial]? 2015
- Financing vaccines for adolescents: a position paper of the society for adolescent health and medicine [editorial]. Journal of Adolescent Health. 48. 2011
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Conference Paper
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Conference Poster
- Elevated blood pressure and risks for progression to hypertension in youth 10-17 years of age [poster] 2019
- Development and validation of a risk equation for appendicitis in children presenting with abdominal pain [poster] 2017
- Racial/ethnic disparities in completion of the routine immunization series by age two [poster] 2017
- Results of a cluster-randomized trial testing the effects of TeenBP, an EHR-based clinical decision support tool, on recognition of adolescent hypertension [poster] 2017
- Incident ADHD diagnosis and use of stimulant medication among youth 10-17 years [poster] 2015
- Relation of change in weight status to the development of hypertension in children and adolescents [poster] 2015
- Implementation of a pediatric prehospital pain management protocol [poster] 2014
- Diagnosis of pediatric hypertension depends on clinical practice guideline definitions [poster] 2013
- Frequency and results of glucose screening in children and adolescents 2007-2011 [poster] 2013
- Impact of BMI and change in BMI on progression from normotension to prehypertension or hypertension in patients ages 3-17 [poster] 2013
- Impact of oral contraceptives on adolescent blood pressure and BMI [poster] 2013
- Impact of oral contraceptives on adolescent blood pressure and BMI [poster] 2013
- Prehypertension and hypertension in community-based pediatric practice [poster] 2013
- Prevalence of obesity and extreme obesity in children aged three to five years [poster] 2013
- Acute adverse events following trivalent inactivated influenza vaccine (TIV) in pregnancy [poster] 2012
- Baseline blood pressure among adolescents initiating hormonal contraception [poster] 2012
- Pregnancy among insured adolescents [poster] 2012
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Review
- Priorities Wizard: multisite web-based primary care clinical decision support improved chronic care outcomes with high use rates and high clinician satisfaction rates [review]. EGEMS (Washington, DC). 2019
- Assessing the safety of influenza immunization during pregnancy: the Vaccine Safety Datalink [review]. American Journal of Obstetrics and Gynecology. 2012
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Abstract
- Pediatric appendicitis: trends in emergency department imaging and outcomes in the community setting, 2010-2015 [abstract]. Annals of Emergency Medicine. 2016
- Relation of change in weight status to the development of hypertension in children and adolescents [abstract]. Journal of patient-centered research and reviews. 2016
- Glucose screening and identification of pre-diabetes in children and adolescents 2007-2011 [abstract]. Diabetes. 2013
- Leukotriene inhibitors may be more effective than inhaled corticosteroids in preventing asthma-related exacerbations [abstract]. American Journal of Respiratory and Critical Care Medicine. 2013
- A descriptive study of vaccinations occurring during pregnancy, 2002-2006 [abstract]. Clinical Medicine & Research. 2012
- Identifying pregnancy episodes in the Vaccine Safety Datalink [abstract]. Clinical Medicine & Research. 2012
- Prevalence of HT in children: comparison between task force recommendations and average of multiple measurements over 2 or 4 years [abstract]. Clinical Medicine & Research. 2012
- Prevalence of elevated blood pressure and BMI in U.S. children and adolescents [abstract]. Clinical Medicine & Research. 2012
presentations
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Presentation
- Association of BMI and change in BMI on progression from normotension to prehyertension or hypertension in patients ages 3-17 [presentation]
- Association of BMI and change in BMI on progression from normotension to prehypertension or hypertension in patients ages 3-17 [presentation], Minnesota Health Services Research 17th Annual Conference
- Disparities in pregnancy and birth rates among insured adolescents, 2003-2010 [presentation]
- Evaluation of the association of maternal pertussis vaccination with obstetric events and birth outcomes [presentation]
- Maternal receipt of trivalent inactivated influenza vaccine and risks for preterm or small for gestational age birth [presentation], HMO Research Network 19th Annual Conference: Advancing Research in the Era of Healthcare Reform
- Safety of COVID-19 vaccination in pregnancy - interim data from the Vaccine Safety Datalink [presentation]
- Safety of the seasonal influenza vaccine during pregnancy: maternal health outcomes [presentation]
- Specialty differences in recognizing and managing elevated blood pressures among children and adolescents [presentation]
- Specialty differences in recognizing and managing elevated blood pressures among children and adolescents [presentation]
- Tdap during pregnancy: safety and coverage data from the VSD [presentation]
- Use of electronic clinical decision support to improve clinical recognition of incident elevated blood pressure and return for repeat measurement [presentation]