Overview/research interests: Intranasal delivery of therapeutics to treat and prevent brain damage from Alzheimer’s disease, Parkinson’s disease, stroke, traumatic brain injury, posttraumatic stress disorder, brain tumors and other brain disorders.
- Developed noninvasive, intranasal method for bypassing the blood-brain barrier to target central nervous system therapeutic agents to the brain and spinal cord while reducing system exposure and unwanted side effects
- Developed and patented intranasal insulin and showed that intranasal insulin improves memory in patients with Alzheimer’s disease
- Developed and patented method using intranasal insulin to treat and protect against traumatic brain injury
- Developed method using intranasal insulin to treat and protect against posttraumatic stress disorder
- Developed and patented intranasal deferoxamine for the treatment of Alzheimer’s disease, stroke, Parkinson’s disease, traumatic brain injury and other central nervous system disorders
- Developed and patented intranasal stem cells to bypass the blood-brain barrier and treat Parkinson’s disease, stroke, Alzheimer’s disease and other central nervous system disorders
- Leading expert in why humans uniquely evolved the ability to shed emotional tears in response to stress and the chemistry of emotional tears
- Research has been subject of articles in the New York Times, Wall Street Journal, U.S. News and World Report and numerous other newspapers and magazines
- Interviewed on the Today Show, Good Morning America, 20/20, All Things Considered, the BBC and numerous other TV and radio programs around the world
Current research activities and funding: Intranasal delivery of therapeutics to treat and prevent brain damage from Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, stroke, traumatic brain injury, posttraumatic stress syndrome and other central nervous system disorders.
Geographic Focus
- Minnesota State or Province
Publications in the past 10 years based solely on publications while at HealthPartners. Publications in prior years appear in grey.