Publications included
 

Frey II, William H., PhD uri icon
Sr. Director of Neuroscience Research, Center for Memory & Aging

Positions

Overview/research interests: Intranasal delivery of therapeutics to treat and prevent brain damage from Alzheimer’s disease, Parkinson’s disease, stroke, traumatic brain injury, posttraumatic stress disorder, brain tumors and other brain disorders.

  • Developed noninvasive, intranasal method for bypassing the blood-brain barrier to target central nervous system therapeutic agents to the brain and spinal cord while reducing system exposure and unwanted side effects
  • Developed and patented intranasal insulin and showed that intranasal insulin improves memory in patients with Alzheimer’s disease
  • Developed and patented method using intranasal insulin to treat and protect against traumatic brain injury
  • Developed method using intranasal insulin to treat and protect against posttraumatic stress disorder
  • Developed and patented intranasal deferoxamine for the treatment of Alzheimer’s disease, stroke, Parkinson’s disease, traumatic brain injury and other central nervous system disorders
  • Developed and patented intranasal stem cells to bypass the blood-brain barrier and treat Parkinson’s disease, stroke, Alzheimer’s disease and other central nervous system disorders
  • Leading expert in why humans uniquely evolved the ability to shed emotional tears in response to stress and the chemistry of emotional tears
  • Research has been subject of articles in the New York Times, Wall Street Journal, U.S. News and World Report and numerous other newspapers and magazines
  • Interviewed on the Today Show, Good Morning America, 20/20, All Things Considered, the BBC and numerous other TV and radio programs around the world

Current research activities and funding: Intranasal delivery of therapeutics to treat and prevent brain damage from Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, stroke, traumatic brain injury, posttraumatic stress syndrome and other central nervous system disorders.

Geographic Focus

has collaborator

  • Hanson, Leah R., PhD  Senior Director, Neuroscience Research, and Senior Investigator, HealthPartners Institute