Barclay, Terry R., PhD, LP, Research investigator, Center for Memory & Aging, Regions Hospital 2009 -

Fine, Jared M., PhD, Research Associate 2006 -

Frey II, William H., PhD, Sr. Director 1977 -

Guliani, Gaurav K., MD, Research Investigator

Haake, Bret C., MD, Research Investigator

Hanson, Leah R., PhD, Sr. Director

Herrmann, Amanda A., PhD, Research Associate 2021 -

Jackson, Steven D., MD, Research Investigator

Johnson, Julia C, MD, Research Investigator

Kashyap, Bhavani, MBBS, PhD, Research Associate 2017 -

Nance, Martha A., MD, Research Investigator

Parashos, Sotirios A., MD, PhD, Research Investigator

Wyman-Chick, Kate A., PsyD, ABPP, Investigator and Clinical Neuropsychologist at HealthPartners Neuroscience Center

A case of minimally progressive prodromal Alzheimer's disease. 

Journal of Alzheimer's disease reports. 2023

Abnormal clinical presentation and surgical outcome of an intraventricular cavernoma of the third ventricle. 

BMJ Case Reports. 2023

Implementation and review of the care ecosystem in an integrated healthcare system. 

BMC Geriatrics. 2023

Intranasal insulin treatment partially corrects the altered gene expression profile in the hippocampus of developing rats with perinatal iron deficiency. 

American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 2023

Low-income older adults' vulnerability to anticholinergic medication-associated frailty. 

Drugs and Aging. 2023

Potentially preventable readmissions after acute inpatient rehabilitation. 

American Journal of Physical Medicine and Rehabilitation. 2023

Providing genetic testing and genetic counseling for Parkinson's disease to the community. 

Genetics in Medicine. 2023

Stroke characteristics in a cohort of Hmong American patients. 

Journal of the American Heart Association. 2023

Validation of the Rainbow Model of Integrated Care Measurement Tool in Parkinson's disease. 

Movement Disorders. 2023

A non-invasive direct nose to brain drug delivery platform vs. invasive brain delivery approach: patient-centered care impact analysis. 

Drug delivery. 2022

Assessment of deep brain stimulation candidacy during the COVID-19 pandemic: lessons learned and future directions for neuropsychologists. 

Clinical Neuropsychologist. 2022

Brief visuospatial memory test-revised normative data and form equivalency for adults ages 80-89. 

Clinical Neuropsychologist. 2022

Hip fracture care in Parkinson disease: a retrospective analysis of 1,239 patients. 

Geriatric orthopaedic surgery & rehabilitation. 2022

Intranasal delivery of nanoliposomal SN-38 for treatment of diffuse midline glioma. 

Journal of Neurosurgery. 2022

Intranasal insulin attenuates the long-term adverse effects of neonatal hyperglycemia on the hippocampus in rats. 

Developmental Neuroscience. 2022

Patterns and predictors of extra-corporeal membrane oxygenation related cerebral microbleeds. 

Journal of Stroke and Cerebrovascular Diseases. 2022

Prodromal dementia with Lewy bodies: evolution of symptoms and predictors of dementia onset. 

Journal of Geriatric Psychiatry and Neurology. 2022

Rate and predictors of acute care encounters in the first month after stroke. 

Journal of Stroke and Cerebrovascular Diseases. 2022

Readmission to an acute care hospital during inpatient rehabilitation after stroke. 

American Journal of Physical Medicine and Rehabilitation. 2022

Tools for communicating risk for Parkinson's disease. 

NPJ Parkinson's disease. 2022

A phase II, single-center, randomized, double-blind, placebo-controlled study of the safety and therapeutic efficacy of intranasal glulisine in amnestic mild cognitive impairment and probable mild Alzheimer's disease. 

Drugs and Aging. 2021

A retrospective study evaluating the use of anti-Parkinsonian medications in patients with advanced Parkinson’s disease who are treated with Levodopa-Carbidopa Intestinal Gel and deep brain stimulation: the PD-DUAL Study. 

Neurology. 2021

Barriers to achieving target door-to-needle time in patients treated with IV thrombolysis. 

Healthc Res J. 2021

Cognitive effects of aerobic exercise in Alzheimer's disease: a pilot randomized controlled trial. 

Journal of Alzheimer's Disease. 2021

Comparative effectiveness of intracerebroventricular, intrathecal, and intranasal routes of AAV9 vector administration for genetic therapy of neurologic disease in murine mucopolysaccharidosis type I. 

Frontiers in Molecular Neuroscience. 2021

Longitudinal change in quality of life in neurological disorders measures over 3 years in patients with early Parkinson's disease. 

Movement Disorders. 2021

Losartan improves memory, neurogenesis and cell motility in transgenic Alzheimer's mice. 

Pharmaceuticals (Basel, Switzerland). 2021

Nasal oxytocin for the treatment of psychiatric disorders and pain: achieving meaningful brain concentrations. 

Translational psychiatry. 2021

Neuropsychological test performances and depression in early-stage de novo Parkinson's disease. 

Archives of Clinical Neuropsychology. 2021

A successful quality improvement project for detection and management of acute stroke in hospitalized patients. 

Journal of Neuroscience Nursing. 2020

Antifibrotic effects of amyloid-beta and Its loss in cirrhotic liver. 

Cells. 2020

Cell motility and migration as determinants of stem cell efficacy. 

EBioMedicine. 2020

Double-blind placebo-controlled pilot investigation of the safety of a single dose of rapid-acting intranasal insulin in Down syndrome. 

Drugs in R&D. 2020

Genetic testing for Parkinson disease: current practice, knowledge, and attitudes among US and Canadian movement disorders specialists. 

Genetics in Medicine. 2020

Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non-disease-specific pathway of functional neurologic improvement. 

Brain and behavior. 2020

Intranasal delivery of low-dose insulin ameliorates motor dysfunction and dopaminergic cell death in a 6-OHDA rat model of Parkinson's Disease. 

Neuroscience Letters. 2020

Intranasal delivery of thyroid hormones in MCT8 deficiency. 

PloS One. 2020

Quality improvement in Parkinson's disease: a successful program to enhance timely administration of Levodopa in the hospital. 

Journal of Parkinson's Disease. 2020

Recommendations for the organization of multidisciplinary clinical care teams in Parkinson's disease. 

Journal of Parkinson's Disease. 2020

Tract-specific analysis improves sensitivity of spinal cord diffusion MRI to cross-sectional and longitudinal changes in amyotrophic lateral sclerosis. 

Communications biology. 2020

Transforming dementia care through pragmatic clinical trials embedded in learning healthcare systems. 

Journal of the American Geriatrics Society. 2020

Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform. 

Human Mutation. 2020

Adherence to pharmacotherapy in patients with Parkinson's disease taking three and more daily doses of medication. 

Frontiers in Neurology. 2019

Assessment of the performance of a modified motor scale as applied to juvenile onset Huntington's disease

2019

End-of-life measures in Huntington disease: HDQLIFE meaning and purpose, concern with death and dying, and end of life planning. 

Journal of Neurology. 2019

Feasibility trial of a 10-week adaptive yoga intervention developed for chronic pain patients. 

Pain Management Nursing. 2019

From A to D: a unique case report of recovery after longitudinal myelitis related to lupus. 

American Journal of Physical Medicine and Rehabilitation. 2019

Intranasal coadministration of a diazepam prodrug with a converting enzyme results in rapid absorption of diazepam in rats. 

Journal of Pharmacology and Experimental Therapeutics. 2019

Intranasal losartan decreases perivascular beta amyloid, inflammation, and the decline of neurogenesis in hypertensive rats. 

Neurotherapeutics. 2019

Neurochemical correlates of functional decline in amyotrophic lateral sclerosis. 

Journal of Neurology, Neurosurgery and Psychiatry. 2019

Quantifying intranasally administered deferoxamine in rat brain tissue with mass spectrometry. 

ACS Chemical Neuroscience. 2019

Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial. 

Neurology. 2019

Solitary bone plasmacytoma compression injury disguised as back pain: a case report

2019

Unique case report of a meningeal sarcoma arising during ongoing treatment for progressing intraparenchymal glioma

2019

Use and perceived effectiveness of complementary therapies in Parkinson's disease. 

Parkinsonism & Related Disorders. 2019

A new measure for end of life planning, preparation, and preferences in Huntington disease: HDQLIFE end of life planning. 

Journal of Neurology. 2018

Agreement between clinician-rated versus patient-reported outcomes in Huntington disease. 

Journal of Neurology. 2018

Executive function: responses to aerobic exercise in Alzheimer's disease. 

Geriatric Nursing (New York, N.Y.). 2018

Frontotemporal lobe degeneration as origin of scans without evidence of dopaminergic deficit. 

Frontiers in Neurology. 2018

Neuropsychological test performance in Parkinsonism without dopaminergic deficiency on [123I]-FP-CIT SPECT imaging. 

Journal of the International Neuropsychological Society. 2018

Pharmacokinetics in rat of P8, a peptide drug candidate for the treatment of Alzheimer's disease: stability and delivery to the brain. 

Journal of Alzheimer's disease reports. 2018

Pooled analyses of phase III studies of ADS-5102 (Amantadine) extended-release capsules for dyskinesia in Parkinson's disease. 

CNS drugs. 2018

Rates of abnormally low TOPF word reading scores in individuals failing versus passing performance validity testing. 

Assessment. 2018

Relationships among apathy, health-related quality of life, and function in Huntington's disease. 

Journal of Neuropsychiatry and Clinical Neurosciences. 2018

Rescue therapies for seizure emergencies: new modes of administration. 

Epilepsia. 2018

Screening positive for cognitive impairment: impact on healthcare utilization and provider action in primary and specialty care practices. 

Journal of General Internal Medicine. 2018

Selection of normative group affects rates of mild cognitive impairment in Parkinson's disease. 

Movement Disorders. 2018

What predicts falls in Parkinson disease? Observations from the Parkinson's Foundation registry. 

Neurology. Clinical practice. 2018

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease. 

Neurology. 2017

A survey-based study identifies common but unrecognized symptoms in a large series of juvenile Huntington's disease. 

Neurodegenerative Disease Management. 2017

Diagnostic accuracy and confidence in the clinical detection of cognitive impairment in early-stage Parkinson disease. 

Journal of Geriatric Psychiatry and Neurology. 2017

Factors associated with falling in early, treated Parkinson's disease: The NET-PD LS1 cohort. 

Journal of the Neurological Sciences. 2017

Genetics of Huntington disease. 

Handbook of Clinical Neurology. 2017

Intranasal adeno-associated virus mediated gene delivery and expression of human iduronidase in the central nervous system: a noninvasive and effective approach for prevention of neurologic disease in mucopolysaccharidosis Type I. 

Human Gene Therapy. 2017

Intranasal deferoxamine affects memory loss, oxidation, and the insulin pathway in the streptozotocin rat model of Alzheimer's disease. 

Journal of the Neurological Sciences. 2017

Intranasal delivery of a novel amnion cell secretome prevents neuronal damage and preserves function in a mouse multiple sclerosis model. 

Scientific Reports. 2017

Intranasal insulin treatment of an experimental model of moderate traumatic brain injury. 

Journal of Cerebral Blood Flow and Metabolism. 2017

National randomized controlled trial of virtual house calls for Parkinson disease. 

Neurology. 2017

Oxytocin enhances observational fear in mice. 

Nature communications. 2017

Reliability and validity of the HD-PRO-TriadTM, a health-related quality of life measure designed to assess the symptom triad of Huntington's disease

2017

Research priorities to advance the health and health care of older adults with multiple chronic conditions. 

Journal of the American Geriatrics Society. 2017

Clinical-genetic associations in the Prospective Huntington at Risk Observational Study (PHAROS): implications for clinical trials. 

JAMA neurology. 2016

Cognitive function in 1736 participants in NINDS Exploratory Trials in PD Long-term Study-1. 

Parkinsonism & Related Disorders. 2016

Food consumption and activity levels increase in rats following intranasal Hypocretin-1. 

Neuroscience Letters. 2016

HDQLIFE: development and assessment of health-related quality of life in Huntington disease (HD). 

Quality of Life Research. 2016

HDQLIFE: the development of two new computer adaptive tests for use in Huntington disease, speech difficulties, and swallowing difficulties. 

Quality of Life Research. 2016

Health care delivery practices in Huntington's disease specialty clinics: an international survey

2016

Intranasal delivery of obidoxime to the brain prevents mortality and CNS damage from organophosphate poisoning. 

Neurotoxicology. 2016

Intranasal drug delivery bypasses the blood–brain barrier

2016

MECR mutations cause childhood-onset dystonia and optic atrophy, a mitochondrial fatty acid synthesis disorder. 

American Journal of Human Genetics. 2016

National randomized controlled trial of virtual house calls for people with Parkinson's disease: Interest and barriers. 

Telemedicine Journal and e-Health. 2016

New measures to capture end of life concerns in Huntington disease: Meaning and Purpose and Concern with Death and Dying from HDQLIFE (a patient-reported outcomes measurement system). 

Quality of Life Research. 2016

Oxytocin receptor: expression in the trigeminal nociceptive system and potential role in the treatment of headache disorders. 

Cephalalgia. 2016

Routine cognitive screening in a neurology practice: effect on physician behavior. 

Neurology. Clinical practice. 2016

The impact of oculomotor functioning on neuropsychological performance in Huntington disease. 

Journal of Clinical and Experimental Neuropsychology. 2016

Can biomarkers differentiate pain and no pain subgroups of nonverbal children with cerebral palsy? A preliminary investigation based on noninvasive saliva sampling. 

Pain Medicine. 2015

Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial. 

JAMA. 2015

Huntington disease

2015

Intranasal deferoxamine engages multiple pathways to decrease memory loss in the APP/PS1 model of amyloid accumulation. 

Neuroscience Letters. 2015

Intranasal delivery of therapeutic neural stem cells to target intracerebral glioma

2015

Managing residents with Parkinson's disease in long-term care

2015

Motor onset and diagnosis in Huntington disease using the diagnostic confidence level. 

Journal of Neurology. 2015

Multivariate clustering of progression profiles reveals different depression patterns in prodromal Huntington disease. 

Neuropsychology. 2015

Noninvasive intranasal stem cells bypass the blood-brain barrier to target the brain to treat Parkinson's disease, stroke, MS, brain tumors, cerebral ischemia, Alzheimer's and other CNS disorders

2015

Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomised, double-blind, placebo-controlled trial. 

Lancet Neurology. 2015

Sex differences in clinical features of early, treated Parkinson's disease. 

PloS One. 2015

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study. 

Movement Disorders. 2015

Validation of an ambulatory capacity measure in Parkinson disease: a construct derived from the Unified Parkinson's Disease Rating Scale. 

Journal of Parkinson's Disease. 2015

. 2008;157:908-25]. 

Neuroscience. 2014

. 2012 Jan 11;8:3]. 

Molecular Pain. 2014

A single-dose pilot trial of intranasal rapid-acting insulin in apolipoprotein e4 carriers with mild-moderate Alzheimer's disease. 

CNS drugs. 2014

Clinical and biomarker changes in premanifest Huntington disease show trial feasibility: a decade of the PREDICT-HD Study. 

Frontiers in Aging Neuroscience. 2014

Clinical, demographic, and pharmacologic features of nursing home residents with Huntington's disease. 

Journal of the American Medical Directors Association. 2014

Cognitive and motor function in long-duration PARKIN-associated Parkinson disease. 

JAMA neurology. 2014

Experience, knowledge, and opinions about childhood genetic testing in Batten disease. 

Molecular Genetics and Metabolism. 2014

Eye-specific gene expression following embryonic ethanol exposure in zebrafish: roles for heat shock factor 1. 

Reproductive Toxicology. 2014

Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. 

JAMA neurology. 2014

Intranasal delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer's and Parkinson's disease. 

Cell Transplantation. 2014

Intranasal delivery, a quick and effective way to deliver therapeutics to the brain. 

AAPS (American Association of Pharmaceutical Scientists) Newsmagazine. 2014

Intranasal insulin: a potential therapeutic for post-traumatic stress disorder and Alzheimer's. 

Minn Physician. 2014

Intranasally-administered deferoxamine mitigates toxicity of 6-OHDA in a rat model of Parkinsons disease. 

Brain Research. 2014

Measuring disease progression in early Parkinson disease: the National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) experience. 

JAMA neurology. 2014

Mobility, mood and site of care impact health related quality of life in Parkinson's disease. 

Parkinsonism & Related Disorders. 2014

Post-traumatic stress disorder: new approach may help prevent, as well as treat, this devastating disorder

2014

Treatment of myoclonus-dystonia syndrome with tetrabenazine. 

Parkinsonism & Related Disorders. 2014

Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. 

Neurogenetics. 2013

Falls in Parkinson disease: analysis of a large cross-sectional cohort. 

Journal of Parkinson's Disease. 2013

Intranasal administration of CNS therapeutics to awake mice. 

Journal of visualized experiments. 2013

Managing juvenile Huntington's disease. 

Neurodegenerative Disease Management. 2013

Mindfulness-based stress reduction for family caregivers: a randomized controlled trial. 

The Gerontologist. 2013

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. 

Neurology. 2012

Cognitive performance of GBA mutation carriers with early-onset PD: the CORE-PD study. 

Neurology. 2012

Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. 

American Journal of Human Genetics. 2012

Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states: . 

Molecular Pain. 2012

Detection of postoperative sleep-disordered breathing using a portable monitoring device. 

Sleep & breathing = Schlaf & Atmung. 2012

Intranasal deferoxamine improves performance in radial arm water maze, stabilizes HIF-1alpha, and phosphorylates GSK3beta in P301L tau transgenic mice. 

Experimental Brain Research. 2012

Intranasal delivery of deferoxamine reduces spatial memory loss in APP/PS1 mice. 

Drug delivery and translational research. 2012

Intranasal delivery of growth differentiation factor 5 to the central nervous system. 

Drug delivery. 2012

Intranasal delivery of insulin via the olfactory nerve pathway. 

Journal of Pharmacy and Pharmacology. 2012

Intranasal delivery of siRNA to the olfactory bulbs of mice via the olfactory nerve pathway. 

Neuroscience Letters. 2012

Lysosomal enzyme can bypass the blood-brain barrier and reach the CNS following intranasal administration. 

Molecular Genetics and Metabolism. 2012

Population stratification may bias analysis of PGC-1alpha as a modifier of age at Huntington disease motor onset. 

Human Genetics. 2012

Special delivery: intranasal treatments bypass blood-brain barrier to treat Alzheimer's and other brain disorders. 

Minn Physician. 2012

Subacute intranasal administration of tissue plasminogen activator increases functional recovery and axonal remodeling after stroke in rats. 

Neurobiology of Disease. 2012

TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease. 

Biochemical and Biophysical Research Communications. 2012

Ethanol-induced microphthalmia is not mediated by changes in retinoic acid or sonic hedgehog signaling during retinal neurogenesis. 

Alcoholism, Clinical and Experimental Research. 2011

Genetic testing in clinical practice. 

Continuum (Minneapolis, Minn.). 2011

Impulsive behavior and associated clinical variables in Parkinson's disease. 

Psychosomatics. 2011

Intranasal delivery of CNS therapeutics. 

AAPS (American Association of Pharmaceutical Scientists) Newsmagazine. 2011

Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke. 

Journal of Neuroscience. 2011

Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice. 

Journal of Molecular Neuroscience. 2011

Motor end plate innervation loss in diabetes and the role of insulin. 

Journal of Neuropathology and Experimental Neurology. 2011

Neuropsychological profile of parkin mutation carriers with and without Parkinson disease: the CORE-PD Study. 

Journal of the International Neuropsychological Society. 2011

Olfaction in Parkin heterozygotes and compound heterozygotes: the CORE-PD study. 

Neurology. 2011

Recruiting and retaining family caregivers to a randomized controlled trial on mindfulness-based stress reduction. 

Contemporary Clinical Trials. 2011

Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment. 

Brain. 2011

Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease. 

Rejuvenation research. 2011

Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain. 

Molecular Pain. 2010

Challenges assessing clinical endpoints in early Huntington disease. 

Movement Disorders. 2010

Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study. 

Archives of Neurology. 2010

Intranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS. 

Journal of Drug Targeting. 2010

Intranasal delivery of stem cells and genetically engineered cells to the brain. 

Drug Deliv Technol. 2010

Predictors of parkin mutations in early-onset Parkinson disease: the consortium on risk for early-onset Parkinson disease study. 

Archives of Neurology. 2010

Production and fate of the sea lamprey migratory pheromone. 

Fish Physiology and Biochemistry. 2010

Protective effects of intranasal losartan in the APP/PS1 transgenic mouse model of Alzheimer disease. 

Rejuvenation research. 2010

Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease. 

Journal of Clinical and Experimental Neuropsychology. 2010

Sexual and relationship satisfaction among persons with young-onset Parkinson's disease. 

Journal of Sexual Medicine. 2010

Striatal and white matter predictors of estimated diagnosis for Huntington disease. 

Brain Research Bulletin. 2010

Trigeminal pathways deliver a low molecular weight drug from the nose to the brain and orofacial structures. 

Molecular Pharmaceutics. 2010

Determinants of the timing of symptomatic treatment in early Parkinson disease: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience. 

Archives of Neurology. 2009

Genomewide association study for susceptibility genes contributing to familial Parkinson disease. 

Human Genetics. 2009

Human and rodent amyloid-beta peptides differentially bind heme: relevance to the human susceptibility to Alzheimer's disease. 

Archives of Biochemistry and Biophysics. 2009

Intranasal deferoxamine provides increased brain exposure and significant protection in rat ischemic stroke. 

Journal of Pharmacology and Experimental Therapeutics. 2009

Intranasal delivery of cells to the brain. 

European Journal of Cell Biology. 2009

Intranasal drug targeting of hypocretin-1 (orexin-A) to the central nervous system. 

Journal of Pharmaceutical Sciences. 2009

Novel vasoconstrictor formulation to enhance intranasal targeting of neuropeptide therapeutics to the central nervous system. 

Journal of Pharmacology and Experimental Therapeutics. 2009

Prominent phenotypic variability associated with mutations in Progranulin. 

Neurobiology of Aging. 2009

A founding LRRK2 haplotype shared by Tunisian, US, European and Middle Eastern families with Parkinson's disease. 

Parkinsonism & Related Disorders. 2008

Delivery of interferon-beta to the monkey nervous system following intranasal administration. 

Neuroscience. 2008

Delivery of interferon-beta to the monkey nervous system following intranasal administration Neuroscience

2008

Elements of attention in HIV-infected adults: evaluation of an existing model. 

Journal of Clinical and Experimental Neuropsychology. 2008

Elements of attention in HIV-infected adults: evaluation of an existing model J Clin Exp Neuropsychol

2008

Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. 

Neurology. 2008

Intranasal administration delivers peptoids to the rat central nervous system. 

Neuroscience Letters. 2008

Intranasal administration delivers peptoids to the rat central nervous system Neurosci Lett

2008

Intranasal delivery of insulin and a nitric oxide synthase inhibitor in an experimental model of amyotrophic lateral sclerosis Neuroscience

2008

Intranasal delivery of transforming growth factor-beta1 in mice after stroke reduces infarct volume and increases neurogenesis in the subventricular zone. 

BMC Neuroscience. 2008

Intranasal delivery of transforming growth factor-beta1 in mice after stroke reduces infarct volume and increases neurogenesis in the subventricular zone BMC Neurosci

2008

Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults. 

Journal of Alzheimer's Disease. 2008

Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults J Alzheimers Dis

2008

Intranasal insulin prevents cognitive decline, cerebral atrophy and white matter changes in murine type I diabetic encephalopathy Brain

2008

Neurocognition in individuals co-infected with HIV and hepatitis C. 

Journal of Addictive Diseases. 2008

Neurocognition in individuals co-infected with HIV and hepatitis C J Addict Dis

2008

New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163. 

Neuro-Oncology. 2008

New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163 Neuro Oncol

2008

Replication of association between ELAVL4 and Parkinson disease: the GenePD study. 

Human Genetics. 2008

The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study. 

BMC Medicine. 2008

Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease. 

Brain. 2007

Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families. 

Movement Disorders. 2007

Verbal episodic memory declines prior to diagnosis in Huntington's disease. 

Neuropsychologia. 2007

A new locus for dominant hereditary spastic paraplegia maps to chromosome 2p12. 

Neurogenetics. 2006

Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study. 

BMC Medical Genetics. 2006

Mutations in the novel mitochondrial protein REEP1 cause hereditary spastic paraplegia type 31. 

American Journal of Human Genetics. 2006

Falls and injuries resulting from falls among patients with Parkinson's disease and other parkinsonian syndromes. 

Movement Disorders. 2005

Inhibition of ligand binding to G protein-coupled receptors by arachidonic acid. 

Journal of Molecular Neuroscience. 2005

Antigliadin antibodies in Huntington's disease. 

Neurology. 2004

Frequency, reasons, and risk factors of entacapone discontinuation in Parkinson disease. 

Clinical Neuropharmacology. 2004

Intragenic modifiers of hereditary spastic paraplegia due to spastin gene mutations. 

Neurogenetics. 2004

Intranasal administration of interferon beta bypasses the blood-brain barrier to target the central nervous system and cervical lymph nodes: a non-invasive treatment strategy for multiple sclerosis. 

Journal of Neuroimmunology. 2004

The window of opportunity for treatment of focal cerebral ischemic damage with noninvasive intranasal insulin-like growth factor-I in rats. 

Journal of Stroke and Cerebrovascular Diseases. 2004

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. 

American Journal of Human Genetics. 2003

Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. 

Archives of Neurology. 2003

Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. 

Neurology. 2003

Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. 

Human Molecular Genetics. 2003

Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease. 

American Journal of Medical Genetics. Part A. 2003

Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. 

American Journal of Human Genetics. 2003

Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. 

Annals of Neurology. 2003

Predictors of nursing home placement in Huntington disease. 

Neurology. 2003

Seeking clarity through the genetic lens: a work in progress. 

Annals of Neurology. 2003

Inactivation of the human brain muscarinic acetylcholine receptor by oxidative damage catalyzed by a low molecular weight endogenous inhibitor from Alzheimer's brain is prevented by pyrophosphate analogs, bioflavonoids and other antioxidants. 

Brain Research. 2002

Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion. 

Neuroscience Letters. 2001

Inconsistency between severe substantia nigra degeneration with Lewy bodies and clinical parkinsonism in dementia patients: a cliniconeuropathological study. 

Acta Neuropathologica. 2000

Pure hippocampal sclerosis: a rare cause of dementia mimicking Alzheimer's disease. 

Neurology. 2000

Endogenous Alzheimer's brain factor and oxidized glutathione inhibit antagonist binding to the muscarinic receptor. 

Brain Research. 1996

Quantitative analysis of the olfactory pathway for drug delivery to the brain. 

Brain Research. 1995

Clinical characteristics of chronic Creutzfeldt-Jakob disease. 

Journal of Geriatric Psychiatry and Neurology. 1994

Free D-amino acids in human cerebrospinal fluid of Alzheimer disease, multiple sclerosis, and healthy control subjects. 

Molecular and Chemical Neuropathology. 1994

Inhibitor of antagonist binding to the muscarinic receptor is elevated in Alzheimer's brain. 

Brain Research. 1994

Seizures in Alzheimer's disease: clinicopathologic study. 

Journal of Geriatric Psychiatry and Neurology. 1994

Serum cytokine levels in patients with Alzheimer's disease. 

Clinical and Diagnostic Laboratory Immunology. 1994

Transforming growth factor beta in Alzheimer's disease. 

Clinical and Diagnostic Laboratory Immunology. 1994

Two cases of acute anti-GM1 antibody elevations in response to exogenous GM1 without neurological symptoms. 

Journal of Neuroimmunology. 1994

Pick's disease versus Alzheimer's disease: a comparison of clinical characteristics. 

Neurology. 1993

Silica-ELISA method improves detection and quantitation of minor glycolipid components in lipid mixtures and of other antigens. 

Journal of Immunological Methods. 1993

A clinicopathological study of CT scans in Alzheimer's disease. 

Journal of the American Geriatrics Society. 1992

Altered aspartate in Alzheimer neurofibrillary tangles. 

Neurochemical Research. 1992

Clinically diagnosed Alzheimer disease: neuropathologic findings in 650 cases. 

Alzheimer Disease and Associated Disorders. 1992

Deletion in the prion protein gene in a demented patient. 

Human Molecular Genetics. 1992

Multiple sclerosis dementia. 

Neurology. 1992

Racemized D-aspartate in Alzheimer neurofibrillary tangles. 

Brain Research Bulletin. 1992

Risk factors in Alzheimer's disease: a clinicopathologic study. 

Neurology. 1992

Neuropathologically confirmed Alzheimer's disease: clinical diagnoses in 394 cases. 

Journal of Geriatric Psychiatry and Neurology. 1991

Seasonal distribution of births in Alzheimer's disease. 

International Psychogeriatrics. 1991

Dementia lacking distinctive histologic features: a common non-Alzheimer degenerative dementia. 

Neurology. 1990

GM-1 treatment of Alzheimer's disease. A pilot study of safety and efficacy. 

Archives of Neurology. 1990

Immunogold labeling of Alzheimer paired helical filaments with ganglioside MAB A2B5. 

Alzheimer Disease and Associated Disorders. 1990

D-aspartate in human brain. 

Journal of Neurochemistry. 1987

Ganglioside monoclonal antibody (A2B5) labels Alzheimer's neurofibrillary tangles. 

Neurology. 1987

Glial fibrillary acidic protein and Alzheimer's disease. 

Neurochemical Research. 1985

Human brain tubulin purification: decrease in soluble tubulin with age. 

Neurochemical Research. 1985

A comparison of peripheral and central human muscarinic cholinergic receptor affinities for psychotropic drugs. 

Biological Psychiatry. 1982

Postmortem stability of dopamine-sensitive adenylate cyclase, guanylate cyclase, ATPase, and GTPase in rat striatum. 

Journal of Neurochemistry. 1981

Stimulation of guanylate cyclase by EDTA and other chelating agents. 

Biochimica et Biophysica Acta. 1981

Effect of dopamine on activation of rat striatal adenylate cyclase by free Mg2+ and guanyl nucleotides. 

Journal of Neurochemistry. 1980

Recommendations for virtual administration of the PSP Rating Scale [editorial]. 

Movement Disorders.  37. 2022

Intronic pentanucleotide expansion in the replication factor 1 gene (RFC1) is a major cause of adult-onset ataxia [editorial]. 

Neurology. Genetics.  6. 2020

Attention training improves attention and gait in Parkinson disease: a pilot study [editorial]. 

Parkinsonism & Related Disorders.  60. 2019

Defining pediatric Huntington disease: time to abandon the term Juvenile Huntington Disease [editorial]?. 

Movement Disorders.  34. 2019

Parkinson's disease physiotherapy: specialisation adds value [editorial]. 

Lancet Neurology.  17. 2018

The AGING Initiative experience: a call for sustained support for team science networks [editorial]. 

Health research policy and systems.  16. 2018

Challenges of multidisciplinary care in Parkinson's disease [editorial]. 

Lancet Neurology.  12. 2013

Family history in juvenile Huntington disease: do the signs point to "yes" or "very doubtful" [editorial]?. 

Neurology.  80. 2013

Insulin to treat Alzheimer's disease: just follow your nose [editorial]?. 

Expert Review of Clinical Pharmacology.  5. 2012

Posterior cortical atrophy: neuropathological correlations [editorial]. 

Archives of Neurology.  53. 1996

The clinical correlates of high-titer IgG anti-GM1 antibodies [editorial]. 

Annals of Neurology.  36. 1994

The tears of the physician [editorial]. 

JAMA.  263. 1990

Increased glycerol-3-phosphorylcholine in post-mortem Alzheimer's brain [editorial]. 

Lancet (London, England).  1. 1985

Intranasal delivery bypasses the blood-brain barrier to deliver and target insulin and other therapeutics to the central nervous system [invited speaker]

2013

Intranasal delivery bypasses the blood-brain barrier to deliver and target stem cells and other therapeutics to the central nervous system [invited speaker]

2013

Intranasal delivery bypasses the blood-brain barrier to deliver and target therapeutics to the central nervous system [invited speaker]

2013

Intranasal delivery bypasses the blood-brain barrier to deliver and target therapeutics to the central nervous system [invited speaker]

2013

Intranasal delivery bypasses the blood-brain barrier to deliver and target therapeutics to the central nervous system [invited speaker]

2013

Changes in physical activity and nutrition in a behavioral intervention pilot study: Passport to Brain Wellness

2010

Outcomes of an embedded resource and education program for patients and families with memory loss [poster]

2017

Performance on cognitive screening is associated with increased retrospective healthcare utilization [poster]

2015

Pharmacokinetics of a diazepam prodrug/enzyme combination following nasal administration in rats for treatment of seizure emergencies [poster]

2015

Routine cognitive screening in a neurology practice: impact on physician behavior [poster]

2015

The Minnesota Memory Project: baseline data from a longitudinal observational study of aging [poster]

2015

Failure on cognitive screening predicts increased healthcare utilization [poster]

2014

Routine cognitive screening in a general neurology clinic: impact on physician behavior [poster]

2014

Detection of deferoxamine using liquid chromatography/mass spectrometry with electrospray ionization [poster]

2013

Evidence-based provider tools for efficient identification and management of cognitive impairment [poster]

2013

Intranasally administered deferoxamine induces neuroprotection in a 6-OHDA model of Parkinson's disease [poster]

2013

Intranasally administered deferoxamine induces neuroprotection in a 6-OHDA model of Parkinson's disease [poster]

2013

Lavender essential oil improved sleep in residents of a memory care assisted living facility [poster]

2013

The effect of intranasal rapid acting insulin on ApoE4 carriers with mild-moderate Alzheimer's disease [poster]

2013

Feasibility of the mini-cog as a standardized cognitive screen in HealthPartners patients aged 70 and older [poster]

2012

Intranasal deferoxamine treatment in a rat model of Parkinsons disease: preliminary results [poster]

2012

Pedicle screw fixation in cervical trauma [poster]

2012

Specific types of memory complaints may provide an early warning sign of cognitive impairment in community dwelling older adults [poster]

2012

The 6th Vital Sign Project: does cognitive screening in the elderly population improve clinical care [poster]?

2012

Tractography of the human cervical spine nerve roots [poster]

2012

Nasal delivery of lidocaine decreases carrageenan-induced orofacial pain [poster]

2011

Changes in cognitive function and plasma biomarkers in a pilot trial of a multi-domain intervention to prevent cognitive decline [poster]

2010

Clinical features of autopsy confirmed cases of early and late onset Alzheimer's disease [poster]

2010

Intranasal deferoxamine improves memory and decreases GSK3B activity in C57 mice [poster]

2010

Intranasal lidocaine blocks orofacial pain with few behavioral side effects [poster]

2010

MBSR (mindfulness-based stress reduction) for caregivers of people with dementia: the Balance Study [poster]

2010

The Minnesota Memory Project [poster]

2010

Dementia with Lewy bodies: impact of co-pathologies and implications for clinical trial design [review]. 

Alzheimer's & dementia. 2023

Sex differences in dementia with Lewy bodies: focused review of available evidence and future directions [review]. 

Parkinsonism & Related Disorders. 2023

The burden of dementia spectrum disorders and associated comorbid and demographic features [review]. 

Clinics in Geriatric Medicine. 2023

Brain glucose hypometabolism and iron accumulation in different brain regions in Alzheimer's and Parkinson's diseases [review]. 

Pharmaceuticals (Basel, Switzerland). 2022

Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations [review]. 

Translational neurodegeneration. 2022

Mechanisms of intranasal deferoxamine in neurodegenerative and neurovascular disease [review]. 

Pharmaceuticals (Basel, Switzerland). 2021

The global pandemic has permanently changed the state of practice for pre-DBS neuropsychological evaluations [review]. 

Parkinsonism & Related Disorders. 2021

Integrated care in Parkinson's disease: a systematic review and meta-analysis [meta-analysis, review, systematic review]. 

Movement Disorders. 2020

Intranasal insulin: a treatment strategy for addiction [review]. 

Neurotherapeutics. 2020

Does cognitive training prevent cognitive decline: a systematic review [systematic review]. 

Annals of Internal Medicine. 2018

Over-the-counter supplement interventions to prevent cognitive decline, mild cognitive impairment, and clinical Alzheimer-type dementia: a systematic review [systematic review]. 

Annals of Internal Medicine. 2018

Pharmacologic interventions to prevent cognitive decline, mild cognitive impairment, and clinical Alzheimer-type dementia: a systematic review [systematic review]. 

Annals of Internal Medicine. 2018

Physical activity interventions in preventing cognitive decline and Alzheimer-type dementia: a systematic review [systematic review]. 

Annals of Internal Medicine. 2018

Genetic counseling and testing for Huntington's disease: a historical review [review]. 

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 2017

Interventions to prevent age-related cognitive decline, mild cognitive impairment, and clinical Alzheimer's-type dementia [review]

2017

Oxytocin and migraine headache [review]. 

Headache. 2017

Disability rating scales in Parkinson's disease: Critique and recommendations [review]. 

Movement Disorders. 2016

Lacunar stroke in a teenager after minor head trauma: case report and literature review [review]. 

Journal of Child Neurology. 2014

Incomplete nonsense-mediated decay facilitates detection of a multi-exonic deletion mutation in SGCE [review]. 

Clinical Genetics. 2013

Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence [review]. 

CNS drugs. 2013

Intranasal insulin to treat and protect against posttraumatic stress disorder [review]. 

Journal of Nervous and Mental Disease. 2013

Intranasal treatment of central nervous system dysfunction in humans [review]. 

Pharmaceutical Research. 2013

Brain insulin signaling and Alzheimer's disease: current evidence and future directions [review]. 

Molecular Neurobiology. 2012

Intranasal treatment of neurodegenerative diseases and stroke [review]. 

Frontiers in bioscience (Scholar edition). 2012

Therapy in Huntington's disease: where are we [review]?. 

Current Neurology and Neuroscience Reports. 2012

Intranasal insulin as a therapeutic option in the treatment of cognitive impairments [review]. 

Experimental Gerontology. 2011

Intranasal delivery to the central nervous system: mechanisms and experimental considerations [review]. 

Journal of Pharmaceutical Sciences. 2010

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease [review article] BMC Neurosci

2008

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease [review]. 

BMC Neuroscience. 2008

Strategies for intranasal delivery of therapeutics for the prevention and treatment of neuroAIDS [review]. 

Journal of Neuroimmune Pharmacology. 2007

A retrospective study evaluating the use of anti-Parkinsonian medications in patients with advanced Parkinson's disease treated with Levodopa-Carbidopa Intestinal Gel and deep brain stimulation [abstract]. 

Journal of the Neurological Sciences. 2021

IMPACT Learning Health Network: transforming care through embedded pragmatic clinical trials in health care settings that serve people with dementia [abstract]. 

Journal of patient-centered research and reviews. 2021

The NIA IMPACT Collaboratory: transforming dementia care rhrough embedded pragmatic clinical trials [abstract]

2020

Implementation of a mindfulness based dementia-care program within a healthcare system [abstract]. 

Innovation in aging. 2019

Chord Study: the power of music through participation in the giving voice chorus [abstract]. 

Alzheimer's & dementia. 2018

Correlation between evaluation and documentation of neurologic deficit by EMS and ED of patients with acute ischemic stroke [abstract]. 

Neurology. 2018

Analysis of run sheets of EMS serving a metropolitan comprehensive stroke center [abstract]. 

Neurology. 2017

Clinical characteristics and healthcare utilization of Hmong patients presenting with stroke [abstract]. 

Neurology. 2017

Clinical characteristics of Hmong patients presenting with acute ischemic stroke [abstract]. 

Stroke. 2017

Cognitive screening results from the Medicare annual wellness visit in a primary care practice [abstract]. 

Alzheimer's & dementia. 2017

Mindfulness for early Alzheimer's Disease: a pilot study [abstract]. 

Alzheimer's & dementia. 2017

The Twin Cities ALS Research Consortium: a model for regional collaboration in advancing research for people living with ALS [abstract]

2017

Minnesota memory project: use of the Alberta Smell Test in a longitudinal aging cohort [abstract]. 

Alzheimer's & dementia. 2016

Outcomes from routine cognitive screening in a health care system [abstract]. 

Alzheimer's & dementia. 2016

Outcomes of a dementia resource and education program imbedded in a health care system [abstract]. 

Alzheimer's & dementia. 2016

Delivery of therapeutics via the intranasal route for the treatment of neurodegenerative diseases [abstract]. 

Neurotherapeutics. 2015

Changes in physical activity and nutrition in a behavioral intervention pilot study - passport to brain wellness [abstract]. 

Clinical Medicine & Research. 2010

Impact of mind-body and education-based interventions on physiologic markers of chronic stress in family caregivers of dementia patients [abstract]. 

Alternative Therapies in Health and Medicine. 2009

Recruitment and retention of caregivers for patients with dementia: the Balance Study [abstract]. 

Alternative Therapies in Health and Medicine. 2009

Access to youth sports [podcast]

2023

Belonging, burnout and the importance of well-being [podcast]

2023

Black women share pregnancy and post-birth experiences in community circles [podcast]

2023

Changes that improve care and experience [podcast]

2023

City of Saint Paul's diversity and equity efforts [podcast]

2023

Cultural identity and concepts of race in early childhood development [podcast]

2023

Developing DEI initiatives in higher learning [podcast]

2023

Disparities in breast health [podcast]

2023

Diversity, equity, inclusion and anti-racism teams in the workplace [podcast]

2023

Family cancer gene discovered with myGenetics [podcast]

2023

George Floyd global memorial art exhibit [podcast]

2023

Institute for Healthcare Improvement's Equity Action Lab [podcast]

2023

LGBTQ+ colleague resource group creates safe and supportive space [podcast]

2023

Parent navigates allyship [podcast]

2023

The practice of self-care and finding community [podcast]

2023

The realities of responding to microaggressions [podcast]

2023

Connecting with communities [podcast]

2022

Equity and education in the community [podcast]

2022

Equity in the medical workplace [podcast]

2022

Giving back through mentorship [podcast]

2022

Microaggressions: upstander vs. bystander [podcast]

2022

Off the charts: examining the health equity emergency [podcast]

2022

Pathways to racial equity outdoors [podcast]

2022

Penumbra Center for racial healing

2022

The waiting room (on Alzheimer's disease). Broadcast on FM107 Radio.

2016

Caregiver guide for mid to late stage Huntington's disease: for long-term care facilities and in-home care agencies

2015

Methods for protecting and treating traumatic brain injury and concussion with intranasal insulin

2021

Methods for protecting and treating traumatic brain injury, concussion and brain inflammation with intranasal insulin

2021

Methods for protecting and treating traumatic brain injury, concussion and brain inflammation with intranasal insulin

2021

Methods for treating patients with impaired awareness of hypoglycemia

2021

Pharmaceutical compositions and methods for enhancing targeting of therapeutic compounds to the central nervous system

2017

Device and method for delivering therapeutic substances to the maxillary sinus of a patient

2014

Lipid growth factor formulations

2014

Method for protecting and treating at least one muscarinic receptor from dysfunction resulting from free radical damage

2014

Method of treating Parkinson's disease comprising administering deferoxamine (DFO) to the upper one-third of the nasal cavity

2014

Treatment of central nervous system disorders by intranasal administration of immunoglobulin g

2014