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Better care begins here
Our Level 1 Trauma Center and nationally recognized specialty care teams can treat your most complex needs. From our leading-edge treatments to our ongoing research, we’re always working to make your care – and recovery – the best it can be. At Regions Hospital, you’re in excellent hands.
Emergency center

We’re a Level 1 Adult and Pediatric Trauma Center. That means we provide top care for your whole family for injuries and illnesses, from minor to complex.

Patient & guest support

We’re here to help. Get information about preparing for surgery, support services, food and hotel options, guest lounges and more.

Convenient care options

Have a health concern you need treated now, but it’s not life threatening? Visit one of our HealthPartners urgent care clinics or our online Virtuwell clinic.

We’re conveniently located on the edge of downtown St. Paul, Minnesota. You can easily get to us from I-35E or I-94.


Our address is:
640 Jackson Street
St. Paul, MN 55101


Have questions? Call us anytime at 651-254-3456.

Top-level specialty care for all your needs
Older man and woman in the kitchen.
Neuroscience Care
From comprehensive stroke care to brain and spine surgery, our experienced team of neurologists, neurosurgeons and other specialists work together to help you heal.
Lady hugging daughter on deck in wooded area.
Heart Center
Get back to your best life. From simple procedures to complex surgery, our renowned team of heart specialists and surgeons provides top care.
Doctor talking with cancer patient in hospital lobby
Cancer Care Center
Our expert, compassionate care team will develop a treatment plan personalized to your specific needs.
Doctor talking with girl in burn unit of hospital.
Burn Center

As one of the first burn centers in the country, we’ve spent more than 50 years taking care of adults and kids with all kinds of burns and wounds.

Our latest advances

Learn about our ongoing research and how we’re working to give you the best care possible.

Work at Regions

Join an experienced, diverse group of people who go above and beyond to help our patients and each other.

Among the nation's best

Regions is honored to be recognized as a 2020-21 Best Regional Hospital by U.S. News & World Report.

How are we doing?

Your feedback helps us understand what we do well and what we can do even better when it comes to your care.

Patient success stories

When Peggy started experiencing low energy and shortness of breath, she went to Regions. After a successful open-heart surgery, she’s back to herself and feeling better than ever.


Born with a congenital heart defect, Jamal has dealt with heart issues his whole life. When the time came for another surgery, he was glad he chose Regions.


An unexpected diagnosis led Mary to Regions. Hear how her surgeons collaborated to successfully remove a non-cancerous tumor near her spine.